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Brn3a

 

Synaptic Systems offers many antibodies which have been successfully used in retina and vision research. We have added new polyclonal antibodies against Brn3a (#411 003) to our portfolio. Brn3a, also referred to as POU4F1, RGC-1 or Oct-T1, is a transcription factor highly expressed in the developing peripheral sensory nervous system, cells of the B- and T-lymphocytic lineages and in certain regions of the CNS. In the retina, Brn3a is a well-established marker for retinal ganglion cells. These new antibodies function exceptionally well in IHC applications, even at high dilutions.

 
Indirect immunostaining of PFA fixed paraffin mouse retina section with rabbit anti-Brn3a
Indirect immunostaining of PFA fixed flatmound mouse retina with rabbit-anti Brn3a

Figure 1: Brn3a cat. no. 411 003 IHC

Indirect immunostaining of PFA fixed paraffin mouse retina section with rabbit anti-Brn3a (cat. no. 411 003, dilution 1:5000; green). Nuclei have been visualized by DAPI staining (blue).

 

Courtesy: Dr. Hanna Regus-Leydig, Institute of Animal Physiology, Dept. of Biology, University of Erlangen-Nürnberg

Figure 2: Brn3a cat. no. 411 003 IHC

Indirect immunostaining of PFA fixed flatmount mouse retina with rabbit-anti Brn3a (cat. no. 400 003, dilution 1:500; red). Nuclei have been visualized by DAPI staining (blue).

 

Courtesy: Prof. Udo Bartsch, Dept. of Ophthalmogy, University Medical Center Hamburg Eppendorf (UKE)

 

Products

Cat. No. Product Description Application Quantity Price Cart
411 003Brn3a, rabbit, polyclonal, affinity purifiedaffinity IHC IHC-P 50 µg$380.00
411 004Brn3a, Guinea pig, polyclonal, antiserumantiserumIHC IHC-P 100 µl$365.00
411 017Brn3a, rat, monoclonal, purified IgG IgGIHC IHC-P 100 µg$415.00
Result count: 3