Endolymphatic hydrops and cochlear synaptopathy after noise exposure are distinct sequelae of hair cell stereociliary bundle trauma.Fong ML, Paik CB, Quiñones PM, Walker CB, Serafino MJ, Pan DW, Martinez E, Wang J, Phillips GW, Applegate BE, Gratton MA, et al.
Scientific reports (2024) 141: 25660.
160 003 IHC; tested species: mouse
Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn.Gradwell MA, Ozeri-Engelhard N, Eisdorfer JT, Laflamme OD, Gonzalez M, Upadhyay A, Medlock L, Shrier T, Patel KR, Aoki A, Gandhi M, et al.
Neuron (2024) 1128: 1302-1327.e13.
160 003 IHC; tested species: mouse
Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model.Martin Flores N, Podpolny M, McLeod F, Workman I, Crawford K, Ivanov D, Leonenko G, Escott-Price V, Salinas PC
eLife (2024) 12: .
160 003 IHC; tested species: mouse
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease.Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association (2024) : .
160 003 IHC; tested species: mouse
Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.Cordano C, Werneburg S, Abdelhak A, Bennett DJ, Beaudry-Richard A, Duncan GJ, Oertel FC, Boscardin WJ, Yiu HH, Jabassini N, Merritt L, et al.
Cell reports. Medicine (2024) : 101490.
160 003 IHC; tested species: mouse
Demyelination and Na+ Channel Redistribution Underlie Auditory and Vestibular Dysfunction in PMP22-Null Mice.Lee JH, Park S, Perez-Flores MC, Chen Y, Kang M, Choi J, Levine L, Gratton MA, Zhao J, Notterpek L, Yamoah EN, et al.
eNeuro (2024) 112: .
160 003 IHC; tested species: mouse
H-Ras induces exuberant de novo dendritic protrusion growth in mature neurons regardless of cell type.Krüssel S, Deb I, Son S, Ewall G, Chang M, Lee HK, Heo WD, Kwon HB
iScience (2024) 278: 110535.
160 003 IHC; tested species: mouse
Growth hormone promotes myelin repair after chronic hypoxia via triggering pericyte-dependent angiogenesis.Ren SY, Xia Y, Yu B, Lei QJ, Hou PF, Guo S, Wu SL, Liu W, Yang SF, Jiang YB, Chen JF, et al.
Neuron (2024) : .
160 003 IHC; tested species: mouse
P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse.Huang L, Mut-Arbona P, Varga B, Török B, Brunner J, Arszovszki A, Iring A, Kisfali M, Vizi ES, Sperlágh B
iScience (2023) 269: 107560.
160 003 IHC; tested species: mouse
The human milk component myo-inositol promotes neuronal connectivity.Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, et al.
Proceedings of the National Academy of Sciences of the United States of America (2023) 12030: e2221413120.
160 003 ICC, IHC; tested species: human,rat
Preclinical long-term safety of intraspinal transplantation of human dorsal spinal GABA neural progenitor cells.Zheng X, Liu Z, He Z, Xu J, Wang Y, Gong C, Zhang R, Zhang SC, Chen H, Wang W
iScience (2023) 2611: 108306.
160 003 IHC; tested species: rat
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain.Yousefpour N, Locke S, Deamond H, Wang C, Marques L, St-Louis M, Ouellette J, Khoutorsky A, De Koninck Y, Ribeiro-da-Silva A
Cell reports (2023) 421: 112010.
160 003 IHC; tested species: mouse
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, et al.
Nature communications (2023) 141: 459.
160 003 IHC; tested species: mouse
γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons.Meltzer S, Boulanger KC, Chirila AM, Osei-Asante E, DeLisle M, Zhang Q, Kalish BT, Tasnim A, Huey EL, Fuller LC, Flaherty EK, et al.
Neuron (2023) 11111: 1776-1794.e10.
160 003 IHC; tested species: mouse
Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging.Britton R, Wasley T, Harish R, Holz C, Hall J, Yee DC, Melton Witt J, Booth EA, Braithwaite S, Czirr E, Kerrisk Campbell M, et al.
eNeuro (2023) 106: .
160 003 IHC; tested species: mouse
Stress induces behavioral abnormalities by increasing expression of phagocytic receptor, MERTK, in astrocytes to promote synapse phagocytosis.Byun YG, Kim NS, Kim G, Jeon YS, Choi JB, Park CW, Kim K, Jang H, Kim J, Kim E, Han YM, et al.
Immunity (2023) : .
160 003 IHC; tested species: mouse
P2Y6 receptor-dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging.Dundee JM, Puigdellívol M, Butler R, Cockram TOJ, Brown GC
Aging cell (2023) 222: e13761.
160 003 IHC; tested species: mouse
Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.Monsorno K, Ginggen K, Ivanov A, Buckinx A, Lalive AL, Tchenio A, Benson S, Vendrell M, D'Alessandro A, Beule D, Pellerin L, et al.
Nature communications (2023) 141: 5749.
160 003 WB, IHC; tested species: mouse
A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease.Jones ME, Büchler J, Dufor T, Palomer E, Teo S, Martin-Flores N, Boroviak K, Metzakopian E, Gibb A, Salinas PC
Science advances (2023) 92: eabo7421.
160 003 ICC, IHC; tested species: mouse
Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington's disease.Wilton DK, Mastro K, Heller MD, Gergits FW, Willing CR, Fahey JB, Frouin A, Daggett A, Gu X, Kim YA, Faull RLM, et al.
Nature medicine (2023) : .
160 003 IHC; tested species: mouse
Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment.Stillman JM, Mendes Lopes F, Lin JP, Hu K, Reich DS, Schafer DP
Nature communications (2023) 141: 7060.
160 003 IHC; tested species: mouse
Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits.Sanchez-Aguilera A, Masmudi-Martín M, Navas-Olive A, Baena P, Hernández-Oliver C, Priego N, Cordón-Barris L, Alvaro-Espinosa L, García S, Martínez S, Lafarga M, et al.
Cancer cell (2023) 419: 1637-1649.e11.
160 003 IHC; tested species: mouse
The synaptic basis of activity-dependent eye-specific competition.Zhang C, Yadav S, Speer CM
Cell reports (2023) 422: 112085.
160 003 IHC; tested species: mouse
A direct spino-cortical circuit bypassing the thalamus modulates nociception.Cai B, Wu D, Xie H, Chen Y, Wang H, Jin S, Song Y, Li A, Huang S, Wang S, Lu Y, et al.
Cell research (2023) 3310: 775-789.
160 003 IHC; tested species: mouse
Skin-type-dependent development of murine mechanosensory neurons.Koutsioumpa C, Santiago C, Jacobs K, Lehnert BP, Barrera V, Hutchinson JN, Schmelyun D, Lehoczky JA, Paul DL, Ginty DD
Developmental cell (2023) : .
160 003 IHC; tested species: mouse
Mild Traumatic Brain Injury-Induced Disruption of the Blood-Brain Barrier Triggers an Atypical Neuronal Response.Munoz-Ballester C, Mahmutovic D, Rafiqzad Y, Korot A, Robel S
Frontiers in cellular neuroscience (2022) 16: 821885.
160 003 IHC; tested species: mouse
Versatile, do-it-yourself, low-cost spinning disk confocal microscope.Halpern AR, Lee MY, Howard MD, Woodworth MA, Nicovich PR, Vaughan JC
Biomedical optics express (2022) 132: 1102-1120.
160 003 IHC; tested species: mouse
Microglial control of neuronal development via somatic purinergic junctions.Cserép C, Schwarcz AD, Pósfai B, László ZI, Kellermayer A, Környei Z, Kisfali M, Nyerges M, Lele Z, Katona I, Ádám Dénes , et al.
Cell reports (2022) 4012: 111369.
160 003 IHC; tested species: mouse
Microglia maintain the normal structure and function of the hippocampal astrocyte network.Du Y, Brennan FH, Popovich PG, Zhou M
Glia (2022) 707: 1359-1379.
160 003 IHC; tested species: mouse
MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea.Ikäheimo K, Herranen A, Iivanainen V, Lankinen T, Aarnisalo AA, Sivonen V, Patel KA, Demir K, Saarma M, Lindahl M, Pirvola U, et al.
Life science alliance (2022) 52: .
160 003 IHC; tested species: mouse
Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure.Badash I, Quiñones PM, Oghalai KJ, Wang J, Lui CG, Macias-Escriva F, Applegate BE, Oghalai JS
Frontiers in cell and developmental biology (2021) 9: 747870.
160 003 IHC; tested species: mouse
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.Szebényi K, Wenger LMD, Sun Y, Dunn AWE, Limegrover CA, Gibbons GM, Conci E, Paulsen O, Mierau SB, Balmus G, Lakatos A, et al.
Nature neuroscience (2021) 2411: 1542-1554.
160 003 IHC; tested species: human
Acute post-injury blockade of α2δ-1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury.Brennan FH, Noble BT, Wang Y, Guan Z, Davis H, Mo X, Harris C, Eroglu C, Ferguson AR, Popovich PG
Cell reports (2021) 344: 108667.
160 003 IHC; tested species: mouse
Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.Veys L, Devroye J, Lefevere E, Cools L, Vandenabeele M, De Groef L
Frontiers in neuroscience (2021) 15: 726476.
160 003 IHC; tested species: mouse
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.Ding X, Wang J, Huang M, Chen Z, Liu J, Zhang Q, Zhang C, Xiang Y, Zen K, Li L
Nature communications (2021) 121: 2030.
160 003 IHC; tested species: mouse
Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution.Hao X, Allgeyer ES, Lee DR, Antonello J, Watters K, Gerdes JA, Schroeder LK, Bottanelli F, Zhao J, Kidd P, Lessard MD, et al.
Nature methods (2021) 186: 688-693.
160 003 IHC; tested species: mouse
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC
Nature neuroscience (2021) 242: 214-224.
160 003 WB, IHC; tested species: mouse
Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning.Mazaré N, Oudart M, Moulard J, Cheung G, Tortuyaux R, Mailly P, Mazaud D, Bemelmans AP, Boulay AC, Blugeon C, Jourdren L, et al.
Cell reports (2020) 328: 108076.
160 003 IHC; tested species: mouse
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.Cserép C, Pósfai B, Lénárt N, Fekete R, László ZI, Lele Z, Orsolits B, Molnár G, Heindl S, Schwarcz AD, Ujvári K, et al.
Science (New York, N.Y.) (2020) 3676477: 528-537.
160 003 IHC; tested species: mouse
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, et al.
Neurobiology of aging (2020) 89: 89-98.
160 003 IHC; tested species: mouse
REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis.Griffin P, Sheehan PW, Dimitry JM, Guo C, Kanan MF, Lee J, Zhang J, Musiek ES
eLife (2020) 9: .
160 003 IHC; tested species: mouse
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, et al.
Neuron (2020) : .
160 003 IHC; tested species: mouse
Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3.Rodriguez-Jimenez FJ, Vilches A, Perez-Arago MA, Clemente E, Roman R, Leal J, Castro AA, Fustero S, Moreno-Manzano V, Jendelova P, Stojkovic M, et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2020) : .
160 003 IHC; tested species: mouse
Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio.Park HE, Choi D, Park JS, Sim C, Park S, Kang S, Yim H, Lee M, Kim J, Pac J, Rhee K, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2019) 622: 1901673.
160 003 IHC; tested species: mouse
Combining super-resolution microscopy with neuronal network recording using magnesium fluoride thin films as cover layer for multi-electrode array technology.Schmidl L, Schmidl G, Gawlik A, Dellith J, Hübner U, Tympel V, Schmidl F, Plentz J, Geis C, Haselmann H
Scientific reports (2019) 91: 16110.
160 003 IHC; tested species: mouse
Structural and functional connections between the median and the ventrolateral preoptic nucleus.Walter A, van der Spek L, Hardy E, Bemelmans AP, Rouach N, Rancillac A
Brain structure & function (2019) 2249: 3045-3057.
160 003 IHC, iDISCO; tested species: mouse
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.Liang H, Zhao H, Gleichman A, Machnicki M, Telang S, Tang S, Rshtouni M, Ruddell J, Carmichael ST
Proceedings of the National Academy of Sciences of the United States of America (2019) : .
160 003 IHC; tested species: mouse
Imaging tripartite synapses using super-resolution microscopy.Heller JP, Odii T, Zheng K, Rusakov DA
Methods (San Diego, Calif.) (2019) : .
160 003 IHC; tested species: mouse
Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment.Lee J, Lee S, Ryu YJ, Lee D, Kim S, Seo JY, Oh E, Paek SH, Kim SU, Ha CM, Choi SY, et al.
Glia (2019) : .
160 003 IHC; tested species: mouse
Young bone marrow transplantation preserves learning and memory in old mice.Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, et al.
Communications biology (2019) 2: 73.
160 003 IHC; tested species: mouse
Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex.Lee KS, Vandemark K, Mezey D, Shultz N, Fitzpatrick D
Neuron (2019) 1013: 421-428.e5.
160 003 IHC; tested species: mouse
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, et al.
Nature methods (2019) 1611: 1109-1113.
160 003 IHC; tested species: mouse
Restorative effects of human neural stem cell grafts on the primate spinal cord.Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, et al.
Nature medicine (2018) : .
160 003 IHC; tested species: human
Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia.Wang F, Yang YJ, Yang N, Chen XJ, Huang NX, Zhang J, Wu Y, Liu Z, Gao X, Li T, Pan GQ, et al.
Neuron (2018) 994: 689-701.e5.
160 003 IHC; tested species: mouse
CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B, et al.
Neuron (2018) 1001: 120-134.e6.
160 003 IHC; tested species: mouse
The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse.Becker L, Schnee ME, Niwa M, Sun W, Maxeiner S, Talaei S, Kachar B, Rutherford MA, Ricci AJ
eLife (2018) 7: .
160 003 IHC
Iterative expansion microscopy.Chang JB, Chen F, Yoon YG, Jung EE, Babcock H, Kang JS, Asano S, Suk HJ, Pak N, Tillberg PW, Wassie AT, et al.
Nature methods (2017) 146: 593-599.
160 003 IHC; tested species: mouse
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, et al.
Neuron (2017) 935: 1066-1081.e8.
160 003 IHC; tested species: human,mouse
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice.Freria CM, Hall JC, Wei P, Guan Z, McTigue DM, Popovich PG
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3713: 3568-3587.
160 003 IHC; tested species: mouse
Transcriptomic Analysis of Ribosome-Bound mRNA in Cortical Neurites In Vivo.Ouwenga R, Lake AM, O'Brien D, Mogha A, Dani A, Dougherty JD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3736: 8688-8705.
160 003 IHC; tested species: mouse
Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues.Ku T, Swaney J, Park JY, Albanese A, Murray E, Cho JH, Park YG, Mangena V, Chen J, Chung K
Nature biotechnology (2016) 349: 973-81.
160 003 IHC; tested species: mouse
Hippocampal Homer1 levels influence motivational behavior in an operant conditioning task.Wagner KV, Häusl AS, Pöhlmann ML, Hartmann J, Labermaier C, Müller MB, Schmidt MV
PloS one (2014) 91: e85975.
160 003 IHC; tested species: mouse
FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.La Fata G, Gärtner A, Domínguez-Iturza N, Dresselaers T, Dawitz J, Poorthuis RB, Averna M, Himmelreich U, Meredith RM, Achsel T, Dotti CG, et al.
Nature neuroscience (2014) 1712: 1693-700.
160 003 IHC; tested species: mouse
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 339: 3857-64.
160 003 IHC; tested species: mouse
Superresolution imaging of chemical synapses in the brain.Dani A, Huang B, Bergan J, Dulac C, Zhuang X
Neuron (2010) 685: 843-56.
160 003 IHC; tested species: mouse
Delayed appearance of the scaffolding proteins PSD-95 and Homer-1 at the developing rat calyx of Held synapse.Soria Van Hoeve JS, Borst JG
The Journal of comparative neurology (2010) 51822: 4581-90.
160 003 IHC; tested species: rat
[Artificial urinary sphincter in the treatment of neurogenic bladder in children].Guys JM, Faure F, Chiapello A, Monfort G
Chirurgie pediatrique (1988) 294: 178-80.
160 003 ICC, IHC; tested species: rat
Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites.Cserép C, Pósfai B, Schwarcz AD, Dénes Á
eNeuro () 51: .
160 003 IHC; tested species: mouse