Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin.Oevel K, Hohensee S, Kumar A, Rosas-Brugada I, Bartolini F, Soykan T, Haucke V
eLife (2024) 12: .
160 011 ICC; tested species: mouse Glial Cx43 hemichannels and neuronal Panx1 hemichannels and P2X7 receptors orchestrates presynaptic homeostatic plasticity.Rafael A, Tizzoni M, Justet C, Cairus A, Abudara V, Vitureira N
Cellular signalling (2024) : 111113.
160 011 ICC; tested species: rat Astrocyte-secreted neurocan controls inhibitory synapse formation and function.Irala D, Wang S, Sakers K, Nagendren L, Ulloa Severino FP, Bindu DS, Savage JT, Eroglu C
Neuron (2024) 11210: 1657-1675.e10.
160 011 ICC, IHC; tested species: mouse,rat Real-time visualization of structural dynamics of synapses in live cells in vivo.Son S, Nagahama K, Lee J, Jung K, Kwak C, Kim J, Noh YW, Kim E, Lee S, Kwon HB, Heo WD, et al.
Nature methods (2024) : .
160 011 ICC; tested species: rat Sialic acid biosynthesis pathway blockade disturbs neuronal network formation in human iPSC-derived excitatory neurons.Mijdam R, Bijnagte-Schoenmaker C, Dyke E, Moons SJ, Boltje TJ, Nadif Kasri N, Lefeber DJ
Journal of neurochemistry (2023) : .
160 011 ICC; tested species: human Effects of Tropomodulin 2 on Dendritic Spine Reorganization and Dynamics.Kuruba B, Starks N, Josten MR, Naveh O, Wayman G, Mikhaylova M, Kostyukova AS
Biomolecules (2023) 138: .
160 011 ICC; tested species: rat Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation.Sun J, Osenberg S, Irwin A, Ma LH, Lee N, Xiang Y, Li F, Wan YW, Park IH, Maletic-Savatic M, Ballas N, et al.
Cell reports (2023) 421: 111942.
160 011 ICC, IHC; tested species: human An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome.Doorn N, van Hugte EJH, Ciptasari U, Mordelt A, Meijer HGE, Schubert D, Frega M, Nadif Kasri N, van Putten MJAM
Stem cell reports (2023) 188: 1686-1700.
160 011 ICC; tested species: human ANK2 loss-of-function variants are associated with epilepsy, and lead to impaired axon initial segment plasticity and hyperactive network activity in hiPSC-derived neuronal networks.Teunissen MWA, Lewerissa E, van Hugte EJH, Wang S, Ockeloen CW, Koolen DA, Pfundt R, Marcelis CLM, Brilstra E, Howe JL, Scherer SW, et al.
Human molecular genetics (2023) 3214: 2373-2385.
160 011 ICC; tested species: human Vesicular Glutamate Release from Feeder-FreehiPSC-Derived Neurons.Baldassari S, Cervetto C, Amato S, Fruscione F, Balagura G, Pelassa S, Musante I, Iacomino M, Traverso M, Corradi A, Scudieri P, et al.
International journal of molecular sciences (2022) 2318: .
160 011 WB, ICC; tested species: human Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.Azarnia Tehran D, Kochlamazashvili G, Pampaloni NP, Sposini S, Shergill JK, Lehmann M, Pashkova N, Schmidt C, Löwe D, Napieczynska H, Heuser A, et al.
Science advances (2022) 821: eabl5032.
160 011 WB, ICC; tested species: mouse RNA supply drives physiological granule assembly in neurons.Bauer KE, Bargenda N, Schieweck R, Illig C, Segura I, Harner M, Kiebler MA
Nature communications (2022) 131: 2781.
160 011 ICC; tested species: rat Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission.Liu GT, Kochlamazashvili G, Puchkov D, Müller R, Schultz C, Mackintosh AI, Vollweiter D, Haucke V, Soykan T
The EMBO journal (2022) : e109352.
160 011 ICC; tested species: rat SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype.Rigby MJ, Orefice NS, Lawton AJ, Ma M, Shapiro SL, Yi SY, Dieterich IA, Frelka A, Miles HN, Pearce RA, Yu JPJ, et al.
Brain communications (2022) 41: fcac002.
160 011 WB, ICC; tested species: mouse Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines.Konietzny A, Grendel J, Kadek A, Bucher M, Han Y, Hertrich N, Dekkers DHW, Demmers JAA, Grünewald K, Uetrecht C, Mikhaylova M, et al.
The EMBO journal (2022) 414: e106523.
160 011 ICC; tested species: mouse,rat Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons.Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SO
Scientific reports (2021) 111: 17374.
160 011 ICC; tested species: rat Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.Linda K, Lewerissa EI, Verboven AHA, Gabriele M, Frega M, Klein Gunnewiek TM, Devilee L, Ulferts E, Hommersom M, Oudakker A, Schoenmaker C, et al.
Autophagy (2021) : 1-20.
160 011 ICC; tested species: human Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.Buffolo F, Petrosino V, Albini M, Moschetta M, Carlini F, Floss T, Kerlero de Rosbo N, Cesca F, Rocchi A, Uccelli A, Benfenati F, et al.
Cell death & disease (2021) 122: 180.
160 011 ICC; tested species: mouse A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids.Renner H, Grabos M, Becker KJ, Kagermeier TE, Wu J, Otto M, Peischard S, Zeuschner D, TsyTsyura Y, Disse P, Klingauf J, et al.
eLife (2020) 9: .
160 011 ICC; tested species: human Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus.Bayraktar G, Yuanxiang P, Confettura AD, Gomes GM, Raza SA, Stork O, Tajima S, Suetake I, Karpova A, Yildirim F, Kreutz MR, et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2020) 4512: 2120-2130.
160 011 ICC; tested species: rat Circumvention of common labelling artefacts using secondary nanobodies.Sograte-Idrissi S, Schlichthaerle T, Duque-Afonso CJ, Alevra M, Strauss S, Moser T, Jungmann R, Rizzoli SO, Opazo F
Nanoscale (2020) 1218: 10226-10239.
160 011 ICC; tested species: rat Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation.Zhang K, Yu F, Zhu J, Han S, Chen J, Wu X, Chen Y, Shen T, Liao J, Guo W, Yang X, et al.
Cell reports (2020) 313: 107521.
160 011 ICC; tested species: human Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis.De Fusco A, Cerullo MS, Marte A, Michetti C, Romei A, Castroflorio E, Baulac S, Benfenati F
Neurobiology of disease (2020) : 104822.
160 011 ICC; tested species: mouse Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses.Mitlöhner J, Kaushik R, Niekisch H, Blondiaux A, Gee CE, Happel MFK, Gundelfinger E, Dityatev A, Frischknecht R, Seidenbecher C
Cells (2020) 92: .
160 011 ICC; tested species: rat Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters.Trotter JH, Hao J, Maxeiner S, Tsetsenis T, Liu Z, Zhuang X, Südhof TC
The Journal of cell biology (2019) : .
160 011 ICC; tested species: mouse Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course.Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, Pisano T, Aprile D, Cerullo MS, De Fusco A, Giovedì S, et al.
Brain : a journal of neurology (2019) : .
160 011 ICC; tested species: mouse The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators.Persoon CM, Hoogstraaten RI, Nassal JP, van Weering JRT, Kaeser PS, Toonen RF, Verhage M
Neuron (2019) 1046: 1065-1080.e12.
160 011 ICC; tested species: mouse De novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy.Fassio A, Esposito A, Kato M, Saitsu H, Mei D, Marini C, Conti V, Nakashima M, Okamoto N, Olmez Turker A, Albuz B, et al.
Brain : a journal of neurology (2018) 1416: 1703-1718.
160 011 ICC; tested species: rat Constitutive Inactivation of the PRRT2 Gene Alters Short-Term Synaptic Plasticity and Promotes Network Hyperexcitability in Hippocampal Neurons.Valente P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte N, Fruscione F, Castroflorio E, Michetti C, Giansante G, Valtorta F, et al.
Cerebral cortex (New York, N.Y. : 1991) (2018) : .
160 011 ICC; tested species: mouse Adenomatous polyposis coli-stimulated GEF 1 (Asef1) is a negative regulator of excitatory synaptic function.Oh JY, Lim CS, Yoo KS, Park HJ, Park YS, Kim EG, Lee YS, Kaang BK, Kim HK
Journal of neurochemistry (2018) : .
160 011 ICC; tested species: rat Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction.Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR, et al.
EMBO reports (2017) 186: 962-981.
160 011 ICC; tested species: rat Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.Krencik R, Seo K, van Asperen JV, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME, Gan L, et al.
Stem cell reports (2017) 96: 1745-1753.
160 011 ICC Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses.Chiacchiaretta M, Latifi S, Bramini M, Fadda M, Fassio A, Benfenati F, Cesca F
Journal of cell science (2017) 1308: 1435-1449.
160 011 ICC; tested species: mouse Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells.Sloan SA, Darmanis S, Huber N, Khan TA, Birey F, Caneda C, Reimer R, Quake SR, Barres BA, Paşca SP
Neuron (2017) 954: 779-790.e6.
160 011 ICC; tested species: human Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice.Hayashi S, Inoue Y, Hattori S, Kaneko M, Shioi G, Miyakawa T, Takeichi M
Scientific reports (2017) 71: 5801.
160 011 ICC; tested species: mouse Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.Altmüller F, Pothula S, Annamneedi A, Nakhaei-Rad S, Montenegro-Venegas C, Pina-Fernández E, Marini C, Santos M, Schanze D, Montag D, Ahmadian MR, et al.
PLoS genetics (2017) 133: e1006684.
160 011 ICC Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse.Tagliatti E, Fadda M, Falace A, Benfenati F, Fassio A
eLife (2016) 5: .
160 011 ICC; tested species: rat Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A, et al.
The EMBO journal (2015) 348: 1056-77.
160 011 ICC The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.Jaudon F, Raynaud F, Wehrlé R, Bellanger JM, Doulazmi M, Vodjdani G, Gasman S, Fagni L, Dusart I, Debant A, Schmidt S, et al.
Molecular biology of the cell (2015) 2611: 2112-27.
160 011 ICC NMDA-induced accumulation of Shank at the postsynaptic density is mediated by CaMKII.Tao-Cheng JH, Yang Y, Bayer KU, Reese TS, Dosemeci A
Biochemical and biophysical research communications (2014) 4501: 808-11.
160 011 ICC Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.Lauks J, Klemmer P, Farzana F, Karupothula R, Zalm R, Cooke NE, Li KW, Smit AB, Toonen R, Verhage M
PloS one (2012) 76: e39420.
160 011 ICC 
