Cat. No.: 124-01P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 124-01P |
100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control proteins should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
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| Immunogen | Recombinant protein corresponding to PDZ-domain of mouse PSD95 (UniProt Id: Q62108) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Matching antibodies | 124 011, 124 011BT, 124 012, 124 014, 124 008, 124 308, N3783, N3702-AF647-L, N3702-At488-L, N3702-AF568-L |
| Remarks |
This control protein consists of the recombinant protein (PDZ domain of mouse PSD 95) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 124-01p.pdf |
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PSD 95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions.