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Camelid single domain antibodies consist only of one antigen binding site of a Alpaka heavy chain antibody. This antibody is a chimeric construct consisting of the anti-PSD 95 single-domain antibody genetically fused to rabbit IgG1 Fc domain.
|Cat. No. N3783||
lyophilized from PBS
WB: 1 : 1000 gallery
IP: not tested yet
ICC: 1 : 500 (see remarks)
IHC: 1 : 200 up to 1 : 500 (see remarks) gallery
IHC-P/FFPE: 1 : 200 gallery
|Immunogen||Recombinant protein corresponding to AA 68 to 251 from mouse PSD95 (UniProt Id: Q62108)|
Reacts with: mouse (Q62108), rat (P31016).
Other species not tested yet.
|Specificity||Specific for PSD95 K.O.|
|Matching control protein/peptide||124-01P|
This antibody is a chimeric construct consisting of the anti-PSD 95 single-domain antibody genetically fused to rabbit IgG1 Fc domain. It can be used in combination with standard anti-rabbit sescondary reagents.
PSD95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions. Read more: PSD95 single domain antibody