Cat. No.: N3783
Amount: 100 µg
Price:
$515.00
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This product was developed by |
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Camelid single domain antibodies consist only of one antigen binding site of a Alpaka heavy chain antibody. This antibody is a chimeric construct consisting of the anti-PSD 95 single-domain antibody genetically fused to rabbit IgG1 Fc domain.
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| Cat. No. N3783 |
100 µg purified antibody lyophilized from PBS. Reconstitute with 100 µL 50% glycerol and store at -20°C or below. |
| Applications | |
| Clone | 1B2 |
| Subtype | IgG1 |
| Immunogen | Recombinant protein corresponding to AA 68 to 251 from mouse PSD95 (UniProt Id: Q62108) |
| Reactivity |
Reacts with: mouse (Q62108), rat (P31016), human (P78352). Other species not tested yet. |
| Specificity | K.O. validated |
| Matching control protein/peptide | 124-01P |
| Remarks |
This antibody is a chimeric construct consisting of the anti-PSD 95 single-domain antibody 1B2 genetically fused to rabbit IgG1 Fc domain. It can be used in combination with standard anti-rabbit secondary reagents binding the IgG Fc-domain. |
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PSD 95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions.