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Spinophilin - 399-0P

A protein enriched at dendritic spines
control peptide
Cat. No.: 399-0P
Amount: 100 µg
Price: $90.00
Cat. No. 399-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Immunogen Synthetic peptide corresponding to AA 290 to 302 from rat Spinophilin (UniProt Id: O35274)
Matching antibodies 399 003
Data sheet 399-0p.pdf
Cat. No.: 399-0P
Quantity: 100 µg
Price: $90.00
Background
Spinophilin, also known as Neurabin II, is a scaffolding protein enriched in neuronal dendritic spines. It is involved in the targeted loacalization of protein phosphatase-1 (PP1), critical for dopaminergic modulation of glutamate neurotransmission.
More recently it has also been identified as a tumor suppressor. Loss of its function induces a proliferative response by increasing retinoblastoma protein (pRb) phosphorylation.
Protocols