Cat. No.: 197 011BT
Amount: 100 µg
Price:
$465.00
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| Cat. No. 197 011BT |
100 µg purified IgG, lyophilized, labeled with Biotin.
Biotin is a small vitamin B complex molecule. Its small size minimizes interference with antibody binding sites and allows for efficient conjugation without compromising antibody functionality. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Label | biotin |
| Clone | 180C1 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Recombinant protein corresponding to AA 2 to 75 from mouse ZnT3 (UniProt Id: P97441) |
| Reactivity |
Reacts with: rat (Q6QIX3), mouse (P97441). No signal: zebrafish. Other species not tested yet. |
| Matching control protein/peptide | 197-0P |
| Data sheet | 197_011bt.pdf |
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The essential micronutrient zinc plays an important role in many biological processes like growth, development and reproduction. It is found in the active site of many enzymes, where ionization, polarization or replacement of Zn2+ bound water is involved in catalytic reactions. As a charged ion Zn2+ cannot cross biological membranes by simple diffusion and must be transported into or out of cells by specialized transport mechanisms. Four Zn transporter proteins, ZnT 1 to ZnT 4, have been cloned. All of them contain several transmembrane domains and a histidine rich intracellular loop.
In the central nervous system Zn plays important roles in synaptic function and plasticity. At synapses Zn is stored in synaptic vesicles by a mechanism depending on the integral membrane protein ZnT 3.