Cat. No.: 111-2P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 111-2P |
100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized! |
| Applications |
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| Immunogen | Synthetic peptide corresponding to AA 196 to 211 from human SNAP23 (UniProt Id: O00161) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Matching antibodies | 111 202, 111 203, 111 203BT |
| Remarks |
This control peptide consists of the synthetic peptide (DRIDIANARAKKLIDS) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 111-2p.pdf |
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SNAP23 (synaptosome-associated protein of 23 kDa) is an ubiquitously expressed isoform and functional homologue of SNAP25. It is resistant to cleavage by BoNT/A and E. The protein is part of the exocytotic fusion complex (v-SNARE) where it assembles with syntaxin1 and synaptobrevin.
SNAP23 is able to function in regulated exocytosis. Both isoforms may have their own specific binding partners and discrete, albeit mechanistically similar, functional roles within the cell.