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DARPP 32 - 382 004

A dopamine and cAMP regulated phosphoprotein
Polyclonal Guinea pig antiserum
Cat. No.: 382 004
Amount: 100 µl
Price: 350.00 €
Cat. No. 382 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 5000 up to 1 : 10000 gallery  
IHC-P/FFPE: 1 : 500 up to 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 148 to 166 from mouse Darpp32 (UniProt Id: Q60829)
Reactivity Reacts with: mouse (Q6J4I0), rat (Q60829).
Other species not tested yet.
Specificity Specific for DARPP 32.
Matching control protein/peptide 382-0P
Data sheet 382_004.pdf
Cat. No.: 382 004
Quantity: 100 µl
Price: 350.00 €
Background
The dopamine and cAMP regulated phosphoprotein 32 kDa (DARPP 32), also known as PPP1R1B, is phosphorylated in a dopamine dependent manner. Stimulation of the dopamine receptor DRD 1 increases cAMP levels resulting in DARPP 32 phosphorylation. It is a commonly used marker for striatal medium spiny neurons (MSNs).