Tailor-made Antibodies
and Tools for Live Science
Home|||||||Technical Support|

DARPP 32 antibody - 382 004

DARPP32 is a dopamine and cAMP regulated phosphoprotein
Guinea pig polyclonal antiserum
Cat. No.: 382 004
Amount: 100 µl
Price: $350.00
Cat. No. 382 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 5000 up to 1 : 10000 gallery  
IHC-P/FFPE: 1 : 500 up to 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 148 to 166 from mouse Darpp32 (UniProt Id: Q60829)
Reactivity Reacts with: mouse (Q6J4I0), rat (Q60829).
Other species not tested yet.
Specificity Specific for DARPP 32.
Matching control protein/peptide 382-0P
Data sheet 382_004.pdf

References for DARPP 32 - 382 004

Formation of the mouse internal capsule and cerebral peduncle: A pioneering role for striatonigral axons as revealed in Isl1 conditional mutants.
Ehrman JM, Merchan-Sala P, Ehrman L, Chen B, Lim HW, Waclaw RR, Campbell K
The Journal of neuroscience : the official journal of the Society for Neuroscience (2022) : . 382 004 IHC; tested species: mouse
Cat. No.: 382 004
Amount: 100 µl
Price: $350.00
Formation of the mouse internal capsule and cerebral peduncle: A pioneering role for striatonigral axons as revealed in Isl1 conditional mutants.
Ehrman JM, Merchan-Sala P, Ehrman L, Chen B, Lim HW, Waclaw RR, Campbell K
The Journal of neuroscience : the official journal of the Society for Neuroscience (2022) : . 382 004 IHC; tested species: mouse
Background
The dopamine and cAMP regulated phosphoprotein 32 kDa (DARPP 32), also known as PPP1R1B, is phosphorylated in a dopamine dependent manner. Stimulation of the dopamine receptor DRD 1 increases cAMP levels resulting in DARPP 32 phosphorylation. It is a commonly used marker for striatal medium spiny neurons (MSNs).