Cat. No.: 224 208AT488
Amount: 50 µg
Price:
$465.00
|
|
|
| Cat. No. 224 208AT488 |
50 µg purified recombinant IgG, lyophilized, fluorescence-labeled with ATTO® 488.
For many of the fluorescence labeled antibodies conjugated to ATTO® dyes from ATTO®488, ATTO®647N and ATTO®594 dyes are suitable for Stimulated Emission Depletion (STED) microscopy which allows higher resolution imaging compared to confocal laser scanning microscopy. This product or portions thereof is manufactured under license from ATTO-TEC GmbH. Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye. |
| Applications |
IP: N/A ICC: 1 : 500 (see remarks) gallery IHC: not tested yet IHC-P: not tested yet |
| Label | ATTO 488 |
| Clone | Rb53D3 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Synthetic peptide corresponding to AA 28 to 43 from rat GABA-A receptor α1 (UniProt Id: P62813) |
| Reactivity |
Reacts with: mouse (P62812), rat (P62813). Other species not tested yet. |
| Matching control protein/peptide | 224-2P |
| Remarks |
This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 53D3. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. |
| Data sheet | 224_208at488.pdf |
|
|
Gamma-aminobutyric acid type A (GABA-A) receptors mediate the majority of inhibitory neurotransmission in the brain. These receptor proteins are ligand gated chloride ion channels and consist of a pentameric combination of different subunits (alpha, beta, gamma, delta, epsilon and rho). The resulting heterogenous population of GABA-A receptor subtypes are expressed throughout the brain with specific cellular and subcellular expression patterns.