Synaptic Systems - Calretinin

Cat. No.: 214 102

Amount: 200 µl

Price: $360.00

Cat. No. 214 102	200 µl antiserum, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery IP: yes ICC: 1 : 500 gallery IHC: 1 : 500 gallery IHC-P: yes
Immunogen	Full-length recombinant mouse Calretinin (UniProt Id: Q08331)
Reactivity	Reacts with: rat (P47728), mouse (Q08331), chicken, zebrafish, grashopper. Other species not tested yet.
Specificity	K.O. validated PubMed: 30015247
Matching control protein/peptide	214-1P
Data sheet	214_102.pdf

References for Calretinin - 214 102

WB (1)
IHC (8)
IHC-P (1)

Characterization and potential roles of calretinin in rodent spermatozoa.
Dressen C, Schwaller B, Vegh G, Leleux F, Gall D, Lebrun P, Lybaert P
Cell calcium (2018) 74: 94-101. 214 102 WB, IHC-P; KO verified; tested species: mouse,rat

Dendritic Degeneration and Altered Synaptic Innervation of a Central Auditory Neuron During Age-related Hearing Loss.
Wang M, Zhang C, Lin S, Xie R
Neuroscience (2023) 514: 25-37. 214 102 IHC; tested species: mouse

Calretinin-Expressing Synapses Show Improved Synaptic Efficacy with Reduced Asynchronous Release during High-Rate Activity.
Zhang C, Wang M, Lin S, Xie R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2022) 4213: 2729-2742. 214 102 IHC; tested species: mouse

Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon.
van Heusden F, Macey-Dare A, Gordon J, Krajeski R, Sharott A, Ellender T
Cell reports (2021) 354: 109041. 214 102 IHC; tested species: mouse

Biased auditory nerve central synaptopathy is associated with age-related hearing loss.
Wang M, Zhang C, Lin S, Wang Y, Seicol BJ, Ariss RW, Xie R
The Journal of physiology (2021) 5996: 1833-1854. 214 102 IHC; tested species: mouse

Lack of APP and APLP2 in GABAergic Forebrain Neurons Impairs Synaptic Plasticity and Cognition.
Mehr A, Hick M, Ludewig S, Müller M, Herrmann U, von Engelhardt J, Wolfer DP, Korte M, Müller UC
Cerebral cortex (New York, N.Y. : 1991) (2020) 307: 4044-4063. 214 102 IHC; tested species: mouse

A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space.
Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A, et al.
Cell (2019) : . 214 102 IHC; tested species: mouse

Female Mice with Apolipoprotein E4 Domain Interaction Demonstrated Impairments in Spatial Learning and Memory Performance and Disruption of Hippocampal Cyto-Architecture.
Adeosun SO, Hou X, Shi L, Stockmeier CA, Zheng B, Raffai RL, Weisgraber KH, Mosley TH, Ming Wang J
Neurobiology of learning and memory (2019) : . 214 102 IHC; tested species: mouse

Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.
Morello N, Schina R, Pilotto F, Phillips M, Melani R, Plicato O, Pizzorusso T, Pozzo-Miller L, Giustetto M
eNeuro () 55: . 214 102 IHC; tested species: mouse

Cat. No.: 214 102

Amount: 200 µl

Price: $360.00

References
WB (1)
IHC (8)
IHC-P (1)

ICC

IHC

Background

Two isoforms of the vitamin D-dependent Ca-binding proteins have been described so far: Calretinin, also referred to as calbindin D29k, calbindin 2, CALB 2, CAL 2, and CAB 29, and calbindin D28k. These proteins are expressed in cells that have to handle a high calcium influx such as brain, bone, teeth, inner ear and others. Calbindins are believed to regulate cellular activity by suppressing or buffering intracellur calcium.

1 ) Klejbor I et al., J. Physiol. Pharmacol. (2006)
2 ) Haworth R et al., Exp. Toxicol. Pathol. (2006)
3 ) Schmidt H et al., J. Physiol. (Lond.) (2003)
4 ) Barski JJ et al., J. Neurosci. (2003)
5 ) Schwaller B et al., Cerebellum (2002)
6 ) Faucheux C et al., Biochem. J. (1998)
7 ) Lee YS et al., Proc. Natl. Acad. Sci. U.S.A. (1987)

Protocols

AP Detection
ECL Detection
Fluorescent detection
Pre-adsorption protocol

Standard protocol

ICC

PFA fixation
Pre-adsorption protocol

IHC

Free floating
Slide mounted
Tissue preparation
Pre-adsorption protocol

IHC-P

Chromogenic detection
Fluorescent detection
Tissue preparation
Pre-adsorption protocol

OTHER

Preabsorbtion

Other products for this target

Calretinin antibody - 214 102 K.O.

References for Calretinin - 214 102