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MAP 2 - 188 011BT

A major microtubule associated protein
Monoclonal mouse purified IgG
Cat. No.: 188 011BT
Amount: 100 µg
Price: $465.00
Cat. No. 188 011BT 100 µg purified IgG, lyophilized, biotin-labeled. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: 1 : 100 up to 1 : 200 gallery  
IHC-P/FFPE: 1 : 200 gallery  
Label biotin
Clone 198A5
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 2 to 314 from human MAP2-4 hu (UniProt Id: P11137-4)
Epitop Epitop: AA 2 to 309 from human MAP2-4 hu (UniProt Id: P11137-4)
Reactivity Reacts with: human (P11137), rat (P15146), mouse (P20357).
No signal: zebrafish.
Other species not tested yet.
Specificity Specific for MAP 2; recognizes all four isoforms.
Matching control protein/peptide 188-0P
Data sheet 188_011bt.pdf

References for MAP 2 - 188 011BT

Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina.
Michalski D, Härtig W, Krügel K, Edwards RH, Böddener M, Böhme L, Pannicke T, Reichenbach A, Grosche A
Neuroscience (2013) 231: 328-44. 188 011BT IHC
Cat. No.: 188 011BT
Quantity: 100 µg
Price: $465.00
Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina.
Michalski D, Härtig W, Krügel K, Edwards RH, Böddener M, Böhme L, Pannicke T, Reichenbach A, Grosche A
Neuroscience (2013) 231: 328-44. 188 011BT IHC
Background

There are two major classes of heat stable microtubule associated proteins (MAPs): MAP 2, and tau. Both protein classes are involved in the regulation of microtubule polymerization in cells.
Four differentially regulated isoforms of MAP 2 have been described so far.