|Cat. No. 188 011BT||100 µg purified IgG, lyophilized, biotin-labeled. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 100 up to 1 : 500 gallery
IHC: 1 : 100 up to 1 : 200 gallery
IHC-P/FFPE: 1 : 200 gallery
|Subtype||IgG1 (κ light chain)|
|Immunogen||Recombinant protein corresponding to AA 2 to 314 from human MAP2-4 hu (UniProt Id: P11137-4)|
Epitop: AA 2 to 309 from human MAP2-4 hu (UniProt Id: P11137-4)
Reacts with: human (P11137), rat (P15146), mouse (P20357).
No signal: zebrafish.
Other species not tested yet.
|Specificity||Specific for MAP 2; recognizes all four isoforms.|
|Matching control protein/peptide||188-0P|
There are two major classes of heat stable microtubule associated proteins (MAPs): MAP 2, and tau. Both protein classes are involved in the regulation of microtubule polymerization in cells.
Four differentially regulated isoforms of MAP 2 have been described so far.