Tailor-made Antibodies
and Tools for Life Science

MAP2 antibody - 188 006

MAP2 is a major microtubule associated protein in neurons
Chicken polyclonal purified antibody
Cat. No.: 188 006
Amount: 50 µg
Price: $415.00
Cat. No. 188 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to residues near the amino terminus of human Map2 (UniProt Id: P11137-4)
Reactivity Reacts with: rat (P15146), mouse (P20357).
Other species not tested yet.
Specificity Specific for MAP 2; recognizes all four isoforms.
Matching control protein/peptide 188-0P
Remarks

WB: Due to its large size, MAP 2 requires special gel-electrophoresis and Western blot protocols for visualization by immunoblotting. Excellent results can be obtained with the 4-12% TRIS-glycine gradient gels from anamed or NuPAGE 3-8% TRIS-Acetate gradient gels from invitrogen.

Data sheet 188_006.pdf

References for MAP2 - 188 006

Unbiased identification of cell identity in dense mixed neural cultures.
De Beuckeleer S, Van De Looverbosch T, Van Den Daele J, Ponsaerts P, De Vos WH
eLife (2025) 13: . 188 006 ICC; tested species: human
Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions.
Lee PJ, Soares AR, Sun Y, Fai C, Picciotto MR, Guo JU
bioRxiv : the preprint server for biology (2024) : . 188 006 ICC; tested species: mouse
Integrated staging of morphofunctional connectivity in neuronal cultures.
Verstraelen P, Verschuuren M, De Vos WH
STAR protocols (2024) 52: 102957. 188 006 ICC
Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging.
Uzay B, Houcek A, Ma ZZ, Konradi C, Monteggia LM, Kavalali ET
Cell reports (2023) 422: 112042. 188 006 ICC; tested species: human,rat
Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
Hou X, Zhang X, Zou H, Guan M, Fu C, Wang W, Zhang ZR, Geng Y, Chen Y
Neuron (2023) 11112: 1898-1913.e5. 188 006 ICC; tested species: rat
The synaptic vesicle protein Mover/TPRG1L is associated with lipid droplets in astrocytes.
Krohn J, Domart F, Do TT, Dresbach T
Glia (2023) : . 188 006 ICC; tested species: mouse
Temporary alteration of neuronal network communication is a protective response to redox imbalance that requires GPI-anchored prion protein.
Foliaki ST, Wood A, Williams K, Smith A, Walters RO, Baune C, Groveman BR, Haigh CL
Redox biology (2023) 63: 102733. 188 006 ICC; tested species: mouse
Synaptojanin1 modifies endolysosomal parameters in cultured ventral midbrain neurons.
Zhu X, Prakash SS, McAuliffe G, Pan PY
eNeuro (2023) : . 188 006 ICC; tested species: mouse
In Vivo Chronic Brain Cortex Signal Recording Based on a Soft Conductive Hydrogel Biointerface.
Rinoldi C, Ziai Y, Zargarian SS, Nakielski P, Zembrzycki K, Haghighat Bayan MA, Zakrzewska AB, Fiorelli R, Lanzi M, Kostrzewska-Księżyk A, Czajkowski R, et al.
ACS applied materials & interfaces (2022) : . 188 006 ICC; tested species: mouse
Nano-organization of spontaneous GABAergic transmission directs its autonomous function in neuronal signaling.
Guzikowski NJ, Kavalali ET
Cell reports (2022) 406: 111172. 188 006 ICC; tested species: rat
NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury.
Zhou J, Geng Y, Su T, Wang Q, Ren Y, Zhao J, Fu C, Weber M, Lin H, Kaminker JS, Liu N, et al.
Cell reports (2022) 3813: 110557. 188 006 ICC; tested species: mouse
Co-Stimulation of Oxytocin and Arginine-Vasopressin Receptors Affect Hypothalamic Neurospheroid Size.
Salehi MS, Neumann ID, Jurek B, Pandamooz S
International journal of molecular sciences (2021) 2216: . 188 006 ICC; tested species: rat
Neuroligin-1 mediates presynaptic maturation through brain-derived neurotrophic factor signaling.
Petkova-Tuffy A, Gödecke N, Viotti J, Korte M, Dresbach T
BMC biology (2021) 191: 215. 188 006 ICC; tested species: rat
Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.
Alten B, Zhou Q, Shin OH, Esquivies L, Lin PY, White KI, Sun R, Chung WK, Monteggia LM, Brunger AT, Kavalali ET, et al.
Neuron (2020) : . 188 006 ICC; tested species: mouse
High-Content Screening for Protein-Protein Interaction Modulators Using Proximity Ligation Assay in Primary Neurons.
Mendes T, Herledan A, Leroux F, Deprez B, Lambert JC, Kilinc D
Current protocols in cell biology (2020) 861: e100. 188 006 ICC; tested species: rat
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Sartori M, Mendes T, Desai S, Lasorsa A, Herledan A, Malmanche N, Mäkinen P, Marttinen M, Malki I, Chapuis J, Flaig A, et al.
Acta neuropathologica (2019) 1384: 631-652. 188 006 ICC; tested species: rat
High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity.
Verschuuren M, Verstraelen P, García-Díaz Barriga G, Cilissen I, Coninx E, Verslegers M, Larsen PH, Nuydens R, De Vos WH
Acta neuropathologica communications (2019) 71: 6. 188 006 ICC; tested species: mouse
Cat. No.: 188 006
Amount: 50 µg
Price: $415.00