Synaptic Systems

Cat. No.: 165 002

Amount: 200 µl

Price: $360.00

Cat. No. 165 002	200 µl antiserum, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 (AP staining) gallery IP: yes ICC: 1 : 500 gallery IHC: 1 : 500 gallery IHC-P: not tested yet
Immunogen	Recombinant protein corresponding to AA 2 to 185 from mouse Vti1a (UniProt Id: O89116)
Reactivity	Reacts with: rat (Q9JI51), mouse (O89116). Other species not tested yet.
Specificity	K.O. validated
Matching control protein/peptide	165-0P
Data sheet	165_002.pdf

The double deficiency of the SNARE proteins vti1a and vti1b affects neurite outgrowth and signaling in N1E-115 neuroblastoma cells.
Kotschnew K, Winkler D, Reckmann J, Mann C, Schweigert A, Tellkamp G, Müller KM, Fischer von Mollard G
European journal of cell biology (2024) 1034: 151461. 165 002 WB; tested species: mouse

Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
Xie YX, Naseri NN, Fels J, Kharel P, Na Y, Lane D, Burré J, Sharma M
Nature communications (2022) 131: 4918. 165 002 WB; tested species: mouse

VAMP4 maintains a Ca2+-sensitive pool of spontaneously recycling synaptic vesicles.
Lin PY, Chanaday NL, Horvath PM, Ramirez DMO, Monteggia LM, Kavalali ET
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 165 002 WB; tested species: rat

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, et al.
The Journal of biological chemistry (2016) 2913: 1320-35. 165 002 WB

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 165 002 WB

Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport.
Steuble M, Diep TM, Schätzle P, Ludwig A, Tagaya M, Kunz B, Sonderegger P
Biology open (2012) 18: 761-74. 165 002 WB

Cat. No.: 165 002

Amount: 200 µl

Price: $360.00

ICC

IHC

Background

Protocols

Vti1a antibody - 165 002 K.O.