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Vti1b antibody - 164 002

Vti1b is a SNARE protein involved in endosomal fusion events
Polyclonal rabbit antiserum
Cat. No.: 164 002
Amount: 200 µl
Price: $350.00
Cat. No. 164 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 1000 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 250 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 206 from rat Vti1b (UniProt Id: P58200)
Reactivity Reacts with: human (Q9UEU0), rat (P58200), mouse (O88384).
No signal: zebrafish.
Other species not tested yet.
Specificity Specific for vti1b. K.O. PubMed: 30335684
Matching control protein/peptide 164-0P
Data sheet 164_002.pdf

References for Vti1b - 164 002

Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells.
Zhou Y, Zhao R, Schwarz EC, Akbar R, Kaba M, Pattu V, Helms V, Rieger H, Nunes-Hasler P, Qu B
Journal of immunology (Baltimore, Md. : 1950) (2020) : . 164 002 WB, ICC; KD verified; tested species: human
SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy.
Ullrich M, Aßmus B, Augustin AM, Häbich H, Abeßer M, Martin Machado J, Werner F, Erkens R, Arias-Loza AP, Umbenhauer S, Wagner H, et al.
Journal of molecular and cellular cardiology (2019) 129: 13-26. 164 002 WB; tested species: mouse
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 164 002 WB; tested species: human
Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Golebiewska EM, Harper MT, Williams CM, Savage JS, Goggs R, Fischer von Mollard G, Poole AW
The Journal of biological chemistry (2015) 2903: 1536-45. 164 002 WB
Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission.
Ramirez DM, Khvotchev M, Trauterman B, Kavalali ET
Neuron (2012) 731: 121-34. 164 002 WB; tested species: rat
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.
Fraldi A, Annunziata F, Lombardi A, Kaiser HJ, Medina DL, Spampanato C, Fedele AO, Polishchuk R, Sorrentino NC, Simons K, Ballabio A, et al.
The EMBO journal (2010) 2921: 3607-20. 164 002 WB, ICC; tested species: mouse
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells.
Zhou Y, Zhao R, Schwarz EC, Akbar R, Kaba M, Pattu V, Helms V, Rieger H, Nunes-Hasler P, Qu B
Journal of immunology (Baltimore, Md. : 1950) (2020) : . 164 002 WB, ICC; KD verified; tested species: human
Vti1b promotes TRPV1 sensitization during inflammatory pain.
Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S, Gomez-Varela D, Schmidt M
Pain (2019) 1602: 508-527. 164 002 ICC, IHC; KO,KD verified; tested species: mouse
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 164 002 ICC; tested species: human
Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes.
Qu B, Pattu V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, et al.
Journal of immunology (Baltimore, Md. : 1950) (2011) 18612: 6894-904. 164 002 ICC
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.
Fraldi A, Annunziata F, Lombardi A, Kaiser HJ, Medina DL, Spampanato C, Fedele AO, Polishchuk R, Sorrentino NC, Simons K, Ballabio A, et al.
The EMBO journal (2010) 2921: 3607-20. 164 002 WB, ICC; tested species: mouse
Vti1b promotes TRPV1 sensitization during inflammatory pain.
Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S, Gomez-Varela D, Schmidt M
Pain (2019) 1602: 508-527. 164 002 ICC, IHC; KO,KD verified; tested species: mouse
Cat. No.: 164 002
Quantity: 200 µl
Price: $350.00
Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells.
Zhou Y, Zhao R, Schwarz EC, Akbar R, Kaba M, Pattu V, Helms V, Rieger H, Nunes-Hasler P, Qu B
Journal of immunology (Baltimore, Md. : 1950) (2020) : . 164 002 WB, ICC; KD verified; tested species: human
SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy.
Ullrich M, Aßmus B, Augustin AM, Häbich H, Abeßer M, Martin Machado J, Werner F, Erkens R, Arias-Loza AP, Umbenhauer S, Wagner H, et al.
Journal of molecular and cellular cardiology (2019) 129: 13-26. 164 002 WB; tested species: mouse
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 164 002 WB; tested species: human
Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Golebiewska EM, Harper MT, Williams CM, Savage JS, Goggs R, Fischer von Mollard G, Poole AW
The Journal of biological chemistry (2015) 2903: 1536-45. 164 002 WB
Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission.
Ramirez DM, Khvotchev M, Trauterman B, Kavalali ET
Neuron (2012) 731: 121-34. 164 002 WB; tested species: rat
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.
Fraldi A, Annunziata F, Lombardi A, Kaiser HJ, Medina DL, Spampanato C, Fedele AO, Polishchuk R, Sorrentino NC, Simons K, Ballabio A, et al.
The EMBO journal (2010) 2921: 3607-20. 164 002 WB, ICC; tested species: mouse
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells.
Zhou Y, Zhao R, Schwarz EC, Akbar R, Kaba M, Pattu V, Helms V, Rieger H, Nunes-Hasler P, Qu B
Journal of immunology (Baltimore, Md. : 1950) (2020) : . 164 002 WB, ICC; KD verified; tested species: human
Vti1b promotes TRPV1 sensitization during inflammatory pain.
Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S, Gomez-Varela D, Schmidt M
Pain (2019) 1602: 508-527. 164 002 ICC, IHC; KO,KD verified; tested species: mouse
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 164 002 ICC; tested species: human
Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes.
Qu B, Pattu V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, et al.
Journal of immunology (Baltimore, Md. : 1950) (2011) 18612: 6894-904. 164 002 ICC
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 164 002 WB, IP, ICC
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.
Fraldi A, Annunziata F, Lombardi A, Kaiser HJ, Medina DL, Spampanato C, Fedele AO, Polishchuk R, Sorrentino NC, Simons K, Ballabio A, et al.
The EMBO journal (2010) 2921: 3607-20. 164 002 WB, ICC; tested species: mouse
Vti1b promotes TRPV1 sensitization during inflammatory pain.
Sondermann JR, Barry AM, Jahn O, Michel N, Abdelaziz R, Kügler S, Gomez-Varela D, Schmidt M
Pain (2019) 1602: 508-527. 164 002 ICC, IHC; KO,KD verified; tested species: mouse