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Home > Products > 160 022

Homer1b/c antibody - 160 022

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Rabbit polyclonal antiserum
Cat. No.: 160 022
Amount: 200 µl
Price: $360.00
Cat. No. 160 022 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to the c-terminal half of human Homer 1b (UniProt Id: Q86YM7-1)
Reactivity Reacts with: rat (Q9Z214), mouse, human (Q86YM7-1).
Other species not tested yet.
Specificity Specific for homer 1b and 1c; no cross-reactivity to homer 1a.
Matching control protein/peptide 160-02P
Data sheet 160_022.pdf

References for Homer1b/c - 160 022

Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice.
Atanasova E, Arévalo AP, Graf I, Zhang R, Bockmann J, Lutz AK, Boeckers TM
Molecular autism (2023) 141: 1. 160 022 WB; tested species: mouse
Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism.
Grabrucker S, Pagano J, Schweizer J, Urrutia-Ruiz C, Schön M, Thome K, Ehret G, Grabrucker AM, Zhang R, Hengerer B, Bockmann J, et al.
The EMBO journal (2021) : e104267. 160 022 WB; tested species: mouse
Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 Deletion.
Song TJ, Lan XY, Wei MP, Zhai FJ, Boeckers TM, Wang JN, Yuan S, Jin MY, Xie YF, Dang WW, Zhang C, et al.
Frontiers in cellular neuroscience (2019) 13: 111. 160 022 WB; tested species: rat
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.
Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, et al.
Molecular psychiatry (2017) 225: 689-702. 160 022 WB; tested species: mouse
Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.
Mei Y, Monteiro P, Zhou Y, Kim JA, Gao X, Fu Z, Feng G
Nature (2016) 5307591: 481-4. 160 022 WB; tested species: mouse
Cat. No.: 160 022
Amount: 200 µl
Price: $360.00
WB
ICC
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