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Homer 1 antibody - 160 005

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Guinea pig polyclonal purified antibody
Cat. No.: 160 005
Amount: 100 µl
Price: $450.00
Cat. No. 160 005 100 µl specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: 1 : 1000 (AP-staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to the c-terminal half of human Homer 1b. (UniProt Id: Q86YM7)
Reactivity Reacts with: mouse (Q9Z2Y3), rat (Q9Z214), human (Q86YM7).
Other species not tested yet.
Specificity Specific for Homer 1. According to Soloviev et al. (2000), aa 1 - 180 are present in isoforms a, b, c and d.
Matching control protein/peptide 160-0P
Data sheet 160_005.pdf
Cat. No.: 160 005
Amount: 100 µl
Price: $450.00
Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.