Tailor-made Antibodies
and Tools for Life Science

Gephyrin antibody - 147 208 K.O.

Gephyrin is a scaffolding protein associated with inhibitory neurotransmitter receptors
Rat monoclonal recombinant IgG
Cat. No.: 147 208
Amount: 50 µg
Price: $420.00
Cat. No. 147 208 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended (see remarks)
IP: not recommended (see remarks)
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P: not recommended
Clone RtmAb7a
Subtype IgG1 (κ light chain)
Immunogen Nativ Protein corresponding to AA 1 to 768 from rat Gephyrin (UniProt Id: Q03555)
Epitop AA 264 to 276 from rat Gephyrin (UniProt Id: Q03555)
Reactivity Reacts with: human (Q9NQX3), rat (Q03555), mouse (Q8BUV3), pig, goldfish, zebrafish.
Other species not tested yet.
Specificity Specific for the brain specific 93 kDa splice variant phosphorylated at Ser-270. K.O. validated
Remarks

This antibody is a chimeric antibody based on the well known monoclonal mouse antibody mAb7a. The constant regions of the heavy and light chains have been replaced with rat specific sequences. The antibody can therefore be used with standard anti-rat secondary reagents.
The antibody has been expressed in mammalian cells.
WB: Clone 3B11 (cat. no. 147 111) is highly recommended.
IP: Clone 3B11 (cat. no. 147 111) highly recommended.

Data sheet 147_208.pdf

References for Gephyrin - 147 208

RPS23RG1 inhibits SORT1-mediated lysosomal degradation of MDGA2 to protect against autism.
Huo Y, Zhao D, Zhu X, Zheng N, Yang D, Meng J, Chen Y, Zhang YW
Theranostics (2025) 154: 1338-1352. 147 208 WB; tested species: mouse
Cat. No.: 147 208
Amount: 50 µg
Price: $420.00