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VGAT antibody cytoplasmic domain - 131 011

VGAT or VIAAT is the GABA and glycine transporter in the membrane of synaptic vesicles
Monoclonal mouse purified IgG
Cat. No.: 131 011
Amount: 100 µg
Price: $425.00
Cat. No. 131 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 500 up to 1 : 2000 (AP staining) (see remarks) gallery  
IP: yes
ICC: 1 : 200 up to 1 : 1000 gallery  
IHC: 1 : 100 up to 1 : 1000 gallery  
IHC-P/FFPE: 1 : 100 up to 1 : 500 gallery  
EM: yes
FACS: yes
Clone 117G4
Subtype IgG3 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 75 to 87 from rat VGAT (UniProt Id: O35458)
Epitop Epitop: AA 75 to 87 from rat VGAT (UniProt Id: O35458)
Reactivity Reacts with: human (Q9H598), rat (O35458), mouse (O35633), Guinea pig, monkey.
Other species not tested yet.
Specificity Specific for mammalian VGAT. K.O. PubMed: 29431653
Matching control protein/peptide 131-0P
Remarks

WB:  VGAT aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

Data sheet 131_011.pdf

References for VGAT - 131 011

ErbB4 promotes inhibitory synapse formation by cell adhesion, independent of its kinase activity.
Luo B, Liu Z, Lin D, Chen W, Ren D, Yu Z, Xiong M, Zhao C, Fei E, Li B
Translational psychiatry (2021) 111: 361. 131 011 WB, ICC; tested species: mouse
A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome.
Cursano S, Battaglia CR, Urrutia-Ruiz C, Grabrucker S, Schön M, Bockmann J, Braumüller S, Radermacher P, Roselli F, Huber-Lang M, Boeckers TM, et al.
Molecular psychiatry (2020) : . 131 011 WB, IHC; tested species: mouse
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ, et al.
The EMBO journal (2020) : e103358. 131 011 WB; tested species: mouse
Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences.
Scheggi S, Guzzi F, Braccagni G, De Montis MG, Parenti M, Gambarana C
Molecular autism (2020) 111: 62. 131 011 WB; tested species: rat
A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment.
Li SM, Li B, Zhang L, Zhang GF, Sun J, Ji MH, Yang JJ
International immunopharmacology (2020) 87: 106814. 131 011 WB, IHC; tested species: mouse
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, et al.
Epilepsia (2020) : . 131 011 WB, IHC; tested species: mouse
Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain.
Chantranupong L, Saulnier JL, Wang W, Jones DR, Pacold ME, Sabatini BL
eLife (2020) 9: . 131 011 WB; tested species: mouse
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 131 011 WB, ICC; tested species: human
Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP.
Andrés-Benito P, Gelpi E, Povedano M, Santpere G, Ferrer I
Journal of neuropathology and experimental neurology (2018) : . 131 011 WB; tested species: human
Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
Chmielewska JJ, Kuzniewska B, Milek J, Urbanska K, Dziembowska M
Molecular neurobiology (2018) : . 131 011 WB; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks.
Vannini E, Restani L, Pietrasanta M, Panarese A, Mazzoni A, Rossetto O, Middei S, Micera S, Caleo M
Brain structure & function (2016) 2216: 2919-36. 131 011 WB
Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration.
Manca P, Mameli O, Caria MA, Torrejón-Escribano B, Blasi J
Neuroscience (2014) 266: 102-15. 131 011 WB, IHC
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses.
Zander JF, Münster-Wandowski A, Brunk I, Pahner I, Gómez-Lira G, Heinemann U, Gutiérrez R, Laube G, Ahnert-Hilger G
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 3022: 7634-45. 131 011 IP
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
ErbB4 promotes inhibitory synapse formation by cell adhesion, independent of its kinase activity.
Luo B, Liu Z, Lin D, Chen W, Ren D, Yu Z, Xiong M, Zhao C, Fei E, Li B
Translational psychiatry (2021) 111: 361. 131 011 WB, ICC; tested species: mouse
Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis.
Daura E, Tegelberg S, Yoshihara M, Jackson C, Simonetti F, Aksentjeff K, Ezer S, Hakala P, Katayama S, Kere J, Lehesjoki AE, et al.
Neurobiology of disease (2021) : 105418. 131 011 ICC; tested species: mouse
VAMP4 maintains a Ca2+-sensitive pool of spontaneously recycling synaptic vesicles.
Lin PY, Chanaday NL, Horvath PM, Ramirez DMO, Monteggia LM, Kavalali ET
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 131 011 ICC; tested species: rat
BDNF impact on synaptic dynamics: extra or intracellular long-term release differently regulates cultured hippocampal synapses.
Rauti R, Cellot G, D'Andrea P, Colliva A, Scaini D, Tongiorgi E, Ballerini L
Molecular brain (2020) 131: 43. 131 011 ICC; tested species: rat
Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment.
Pan-Vazquez A, Wefelmeyer W, Gonzalez Sabater V, Neves G, Burrone J
Neuron (2020) : . 131 011 ICC, IHC; tested species: mouse
Central Cholinergic Synapse Formation in Optimized Primary Septal-Hippocampal Co-cultures.
Djemil S, Ressel CR, Abdel-Ghani M, Schneeweis AK, Pak DTS
Cellular and molecular neurobiology (2020) : . 131 011 ICC; tested species: rat
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids.
Renner H, Grabos M, Becker KJ, Kagermeier TE, Wu J, Otto M, Peischard S, Zeuschner D, TsyTsyura Y, Disse P, Klingauf J, et al.
eLife (2020) 9: . 131 011 ICC; tested species: human
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 131 011 WB, ICC; tested species: human
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 131 011 ICC; tested species: human
Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output.
Paraskevopoulou F, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3923: 4448-4460. 131 011 ICC; tested species: mouse
Differential Properties of the Synaptogenic Activities of the Neurexin Ligands Neuroligin1 and LRRTM2.
Dagar S, Gottmann K
Frontiers in molecular neuroscience (2019) 12: 269. 131 011 ICC; tested species: mouse
TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, et al.
Cell reports (2019) 295: 1130-1146.e8. 131 011 ICC; tested species: mouse
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, et al.
Science (New York, N.Y.) (2018) : . 131 011 ICC; tested species: rat
Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.
Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, et al.
Cell (2018) 1733: 735-748.e15. 131 011 ICC; tested species: mouse
MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells.
Tu J, Cao D, Li L, Cheung HH, Chan WY
FEBS open bio (2018) 84: 502-512. 131 011 ICC; tested species: human
Human iPSC-derived neuronal models for in vitro neurotoxicity assessment.
Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS
Neurotoxicology (2018) 67: 215-225. 131 011 ICC; tested species: human
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, et al.
Molecular systems biology (2018) 147: e8071. 131 011 ICC; tested species: mouse
The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice.
Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T
EBioMedicine (2018) : . 131 011 ICC; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan SK, Diaspro A, Del Bue A, Petrini EM, Barberis A, Cella Zanacchi F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 377: 1747-1756. 131 011 ICC
Inter-Synaptic Lateral Diffusion of GABAA Receptors Shapes Inhibitory Synaptic Currents.
de Luca E, Ravasenga T, Petrini EM, Polenghi A, Nieus T, Guazzi S, Barberis A
Neuron (2017) 951: 63-69.e5. 131 011 ICC; tested species: mouse
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.
Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, et al.
eLife (2017) 6: . 131 011 ICC; tested species: mouse
Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity.
Chacón PJ, del Marco Á, Arévalo Á, Domínguez-Giménez P, García-Segura LM, Rodríguez-Tébar A
Neurobiology of aging (2015) 362: 1057-71. 131 011 ICC, IHC
Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons.
Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ
Molecular brain (2015) 8: 10. 131 011 ICC
Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs.
Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME
Cell (2014) 1575: 1216-29. 131 011 ICC; tested species: mouse
Investigation of synapse formation and function in a glutamatergic-GABAergic two-neuron microcircuit.
Chang CL, Trimbuch T, Chao HT, Jordan JC, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 343: 855-68. 131 011 ICC; tested species: mouse
Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors.
Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I
The Journal of biological chemistry (2014) 28916: 11396-409. 131 011 ICC; tested species: rat
BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons.
Shinoda Y, Ahmed S, Ramachandran B, Bharat V, Brockelt D, Altas B, Dean C
Frontiers in synaptic neuroscience (2014) 6: 27. 131 011 ICC; tested species: rat
Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.
Murata Y, Constantine-Paton M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3311: 5040-52. 131 011 ICC; tested species: mouse,rat
Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons.
Hanson JE, Deng L, Hackos DH, Lo SC, Lauffer BE, Steiner P, Zhou Q
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3314: 5924-9. 131 011 ICC
Minimal Change in the cytoplasmic calcium dynamics in striatal GABAergic neurons of a DYT1 dystonia knock-in mouse model.
Iwabuchi S, Koh JY, Wang K, Ho KW, Harata NC
PloS one (2013) 811: e80793. 131 011 ICC
Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture.
Li H, Hader AT, Han YR, Wong JA, Babiarz J, Ricupero CL, Godfrey SB, Corradi JP, Fennell M, Hart RP, Plummer MR, et al.
Developmental neurobiology (2012) 726: 805-20. 131 011 ICC
Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex.
Takahashi H, Arstikaitis P, Prasad T, Bartlett TE, Wang YT, Murphy TH, Craig AM
Neuron (2011) 692: 287-303. 131 011 ICC; tested species: rat
SV2 mediates entry of tetanus neurotoxin into central neurons.
Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER
PLoS pathogens (2010) 611: e1001207. 131 011 ICC, IHC; tested species: rat
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1.
McClelland AC, Sheffler-Collins SI, Kayser MS, Dalva MB
Proceedings of the National Academy of Sciences of the United States of America (2009) 10648: 20487-92. 131 011 ICC
PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering.
Baer K, Bürli T, Huh KH, Wiesner A, Erb-Vögtli S, Göckeritz-Dujmovic D, Moransard M, Nishimune A, Rees MI, Henley JM, Fritschy JM, et al.
Molecular and cellular neurosciences (2007) 352: 339-55. 131 011 ICC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Maternal Deprivation in Rats Decreases the Expression of Interneuron Markers in the Neocortex and Hippocampus.
Aksic M, Poleksic J, Aleksic D, Petronijevic N, Radonjic NV, Jakovcevski M, Kapor S, Divac N, Filipovic BR, Jakovcevski I
Frontiers in neuroanatomy (2021) 15: 670766. 131 011 IHC; tested species: rat
Early-life sevoflurane exposure impairs fear memory by suppressing extracellular signal-regulated kinase signaling in the bed nucleus of stria terminalis GABAergic neurons.
Zhao XP, Zhong F, Luo RY, Zhang YL, Luo C, Li H, Dai RP
Neuropharmacology (2021) 191: 108584. 131 011 IHC; tested species: mouse
Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration.
van Olst L, Rodriguez-Mogeda C, Picon C, Kiljan S, James RE, Kamermans A, van der Pol SMA, Knoop L, Michailidou I, Drost E, Franssen M, et al.
Acta neuropathologica (2021) 1416: 881-899. 131 011 IHC; tested species: rat
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice.
Frew J, Nygaard HB
Acta neuropathologica communications (2021) 91: 57. 131 011 IHC; tested species: mouse
Aberrant axo-axonic synaptic reorganization in the phosphorylated L1-CAM/calcium channel subunit alpha2 delta-1-containing central terminals of injured c-fibers in the spinal cord of a neuropathic pain model.
Yamanaka H, Okubo M, Kobayashi K, Noguchi K
eNeuro (2021) : . 131 011 IHC; tested species: rat
Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex.
Pintér A, Hevesi Z, Zahola P, Alpár A, Hanics J
Cellular signalling (2020) 74: 109710. 131 011 IHC; tested species: rat
Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment.
Pan-Vazquez A, Wefelmeyer W, Gonzalez Sabater V, Neves G, Burrone J
Neuron (2020) : . 131 011 ICC, IHC; tested species: mouse
Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain.
Lorenzo LE, Godin AG, Ferrini F, Bachand K, Plasencia-Fernandez I, Labrecque S, Girard AA, Boudreau D, Kianicka I, Gagnon M, Doyon N, et al.
Nature communications (2020) 111: 869. 131 011 IHC; tested species: rat
Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal.
Nuzzaci D, Cansell C, Liénard F, Nédélec E, Ben Fradj S, Castel J, Foppen E, Denis R, Grouselle D, Laderrière A, Lemoine A, et al.
Cell reports (2020) 309: 3067-3078.e5. 131 011 IHC; tested species: mouse
Rescue of PB-resistant neonatal seizures with single-dose of small-molecule TrkB antagonist show long-term benefits.
Kang SK, Ammanuel S, Adler DA, Kadam SD
Epilepsy research (2020) 159: 106249. 131 011 IHC; tested species: mouse
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation.
Ji MH, Lei L, Gao DP, Tong JH, Wang Y, Yang JJ
Brain, behavior, and immunity (2020) : . 131 011 IHC; tested species: rat
Microglial mTOR is neuronal protective and anti-epileptogenic in the pilocarpine model of temporal lobe epilepsy.
Zhao XF, Liao Y, Alam MM, Mathur R, Feustel P, Mazurkiewicz JE, Adamo MA, Zhu XC, Huang Y
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 131 011 IHC; tested species: mouse
A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment.
Li SM, Li B, Zhang L, Zhang GF, Sun J, Ji MH, Yang JJ
International immunopharmacology (2020) 87: 106814. 131 011 WB, IHC; tested species: mouse
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, et al.
Epilepsia (2020) : . 131 011 WB, IHC; tested species: mouse
The mouse olfactory peduncle 4: Development of synapses, perineuronal nets, and capillaries.
Collins LN, Brunjes PC
The Journal of comparative neurology (2020) 5284: 637-649. 131 011 IHC; tested species: mouse
Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.
Granger AJ, Wang W, Robertson K, El-Rifai M, Zanello AF, Bistrong K, Saunders A, Chow BW, Nuñez V, Turrero García M, Harwell CC, et al.
eLife (2020) 9: . 131 011 IHC; tested species: mouse
GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy.
Alhourani A, Fish KN, Wozny TA, Sudhakar V, Hamilton RL, Richardson RM
Journal of neurophysiology (2020) 1231: 392-406. 131 011 IHC; tested species: human
A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome.
Cursano S, Battaglia CR, Urrutia-Ruiz C, Grabrucker S, Schön M, Bockmann J, Braumüller S, Radermacher P, Roselli F, Huber-Lang M, Boeckers TM, et al.
Molecular psychiatry (2020) : . 131 011 WB, IHC; tested species: mouse
Synaptic regulation by OPRM1 variants in reward neurocircuitry.
Popova D, Desai N, Blendy JA, Pang ZP
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 131 011 IHC; tested species: mouse
ApoE4 Exacerbates Hippocampal Pathology Following Acute Brain Penetration Injury in Female Mice.
Ben-Moshe H, Luz I, Liraz O, Boehm-Cagan A, Salomon-Zimri S, Michaelson D
Journal of molecular neuroscience : MN (2019) : . 131 011 IHC; tested species: mouse
Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
Grove JCR, Hirano AA, de Los Santos J, McHugh CF, Purohit S, Field GD, Brecha NC, Barnes S
PLoS biology (2019) 174: e3000200. 131 011 IHC; KO verified; tested species: mouse
Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch.
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, Hor CC, Zaher N, Cin M, Slade H, Huang T, et al.
Neuron (2019) 1036: 1135-1149.e6. 131 011 IHC; tested species: mouse
The effects of early life stress on the excitatory/inhibitory balance of the medial prefrontal cortex.
Ohta KI, Suzuki S, Warita K, Sumitani K, Tenkumo C, Ozawa T, Ujihara H, Kusaka T, Miki T
Behavioural brain research (2019) : 112306. 131 011 IHC; tested species: rat
Variable colocalisation of GABAA receptor subunits and glycine receptors on neurons in the human hypoglossal nucleus.
Waldvogel HJ, Biggins FM, Singh A, Arasaratnam CJ, Faull RLM
Journal of chemical neuroanatomy (2019) 97: 99-111. 131 011 IHC; tested species: human
Proliferation of Inhibitory Input to the Substantia Nigra in Experimental Parkinsonism.
Faynveitz A, Lavian H, Jacob A, Korngreen A
Frontiers in cellular neuroscience (2019) 13: 417. 131 011 IHC; tested species: rat
Spinal motor circuit synaptic plasticity after peripheral nerve injury depends on microglia activation and a CCR2 mechanism.
Rotterman TM, Akhter ET, Lane AR, MacPherson KP, Garcia VV, Tansey MG, Alvarez FJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 131 011 IHC; tested species: mouse
Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation.
Andoh M, Shibata K, Okamoto K, Onodera J, Morishita K, Miura Y, Ikegaya Y, Koyama R
Cell reports (2019) 2710: 2817-2825.e5. 131 011 IHC; tested species: mouse
LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing.
Koebis M, Urata S, Shinoda Y, Okabe S, Yamasoba T, Nakao K, Aiba A, Furuichi T
Molecular brain (2019) 121: 20. 131 011 IHC; tested species: mouse
Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function.
Saito Y, Yuan Y, Zucker-Scharff I, Fak JJ, Jereb S, Tajima Y, Licatalosi DD, Darnell RB
Neuron (2019) 1014: 707-720.e5. 131 011 IHC; tested species: mouse
Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes.
Nam MH, Han KS, Lee J, Bae JY, An H, Park S, Oh SJ, Kim E, Hwang E, Bae YC, Lee CJ, et al.
Experimental neurobiology (2018) 272: 120-128. 131 011 IHC; tested species: mouse
Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Zhang B, Gokce O, Hale WD, Brose N, Südhof TC
The Journal of experimental medicine (2018) : . 131 011 IHC; tested species: mouse
Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood.
Tata B, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, et al.
Nature medicine (2018) : . 131 011 IHC; tested species: mouse
Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response.
Jhang J, Lee H, Kang MS, Lee HS, Park H, Han JH
Nature communications (2018) 91: 2744. 131 011 IHC; tested species: mouse
Dopamine receptors in the rat entopeduncular nucleus.
Lavian H, Loewenstern Y, Madar R, Almog M, Bar-Gad I, Okun E, Korngreen A
Brain structure & function (2018) : . 131 011 IHC; tested species: rat
Automated analysis of images for molecular quantification in immunohistochemistry.
Guirado R, Carceller H, Castillo-Gómez E, Castrén E, Nacher J
Heliyon (2018) 46: e00669. 131 011 IHC; tested species: mouse
Regulation of Synapse Development by Vgat Deletion from ErbB4-Positive Interneurons.
Lin TW, Tan Z, Barik A, Yin DM, Brudvik E, Wang H, Xiong WC, Mei L
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3810: 2533-2550. 131 011 IHC; KO verified; tested species: mouse
Input-specific synaptic location and function of the alpha5 GABAA receptor subunit in the mouse CA1 hippocampal neurons.
Magnin E, Francavilla R, Amalyan S, Gervais E, Suzanne David L, Luo X, Topolnik L
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 131 011 IHC; tested species: mouse
The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease-related pathology.
Bar R, Boehm-Cagan A, Luz I, Kleper-Wall Y, Michaelson DM
Alzheimer's & dementia (Amsterdam, Netherlands) (2018) 10: 1-11. 131 011 IHC; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats.
Irintchev M, Guntinas-Lichius O, Irintchev A
Neural plasticity (2018) 2018: 7975013. 131 011 IHC; tested species: rat
Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy.
Li P, Fu X, Smith NA, Ziobro J, Curiel J, Tenga MJ, Martin B, Freedman S, Cea-Del Rio CA, Oboti L, Tsuchida TN, et al.
Neuron (2017) 962: 387-401.e6. 131 011 IHC; tested species: mouse
Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb.
Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K
The Journal of comparative neurology (2017) 5253: 574-591. 131 011 IHC; tested species: mouse
Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain.
Dunn AR, Hoffman CA, Stout KA, Ozawa M, Dhamsania RK, Miller GW
Brain research (2017) : . 131 011 IHC
Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis.
Nemes AD, Ayasoufi K, Ying Z, Zhou QG, Suh H, Najm IM
Scientific reports (2017) 71: 17702. 131 011 IHC; tested species: rat
Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy.
Farhan SMK, Nixon KCJ, Everest M, Edwards TN, Long S, Segal D, Knip MJ, Arts HH, Chakrabarti R, Wang J, Robinson JF, et al.
Human molecular genetics (2017) 2621: 4278-4289. 131 011 IHC; tested species: rat
Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia.
Rocco BR, Lewis DA, Fish KN
Biological psychiatry (2016) 7912: 1006-15. 131 011 IHC
LAMP5 Fine-Tunes GABAergic Synaptic Transmission in Defined Circuits of the Mouse Brain.
Tiveron MC, Beurrier C, Céni C, Andriambao N, Combes A, Koehl M, Maurice N, Gatti E, Abrous DN, Kerkerian-Le Goff L, Pierre P, et al.
PloS one (2016) 116: e0157052. 131 011 IHC
VGluT3-expressing CCK-positive basket cells construct invaginating synapses enriched with endocannabinoid signaling proteins in particular cortical and cortex-like amygdaloid regions of mouse brains.
Omiya Y, Uchigashima M, Konno K, Yamasaki M, Miyazaki T, Yoshida T, Kusumi I, Watanabe M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3510: 4215-28. 131 011 IHC; tested species: mouse
Cerebellar synaptogenesis is compromised in mouse models of DYT1 dystonia.
Vanni V, Puglisi F, Bonsi P, Ponterio G, Maltese M, Pisani A, Mandolesi G
Experimental neurology (2015) 271: 457-67. 131 011 IHC; tested species: mouse
Co-localization of glutamic acid decarboxylase and vesicular GABA transporter in cytochrome oxidase patches of macaque striate cortex.
Adams DL, Economides JR, Horton JC
Visual neuroscience (2015) 32: E026. 131 011 IHC
Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity.
Chacón PJ, del Marco Á, Arévalo Á, Domínguez-Giménez P, García-Segura LM, Rodríguez-Tébar A
Neurobiology of aging (2015) 362: 1057-71. 131 011 ICC, IHC
Structural and functional characterization of dendritic arbors and GABAergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala.
Klenowski PM, Fogarty MJ, Belmer A, Noakes PG, Bellingham MC, Bartlett SE
Journal of neurophysiology (2015) 1142: 942-57. 131 011 IHC
KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ
Nature communications (2015) 6: 6254. 131 011 IHC
A direct GABAergic output from the basal ganglia to frontal cortex.
Saunders A, Oldenburg IA, Berezovskii VK, Johnson CA, Kingery ND, Elliott HL, Xie T, Gerfen CR, Sabatini BL
Nature (2015) 5217550: 85-9. 131 011 IHC
Conditional targeting of medium spiny neurons in the striatal matrix.
Reinius B, Blunder M, Brett FM, Eriksson A, Patra K, Jonsson J, Jazin E, Kullander K
Frontiers in behavioral neuroscience (2015) 9: 71. 131 011 IHC
Reduced cholinergic and glutamatergic synaptic input to regenerated motoneurons after facial nerve repair in rats: potential implications for recovery of motor function.
Raslan A, Ernst P, Werle M, Thieme H, Szameit K, Finkensieper M, Guntinas-Lichius O, Irintchev A
Brain structure & function (2014) 2193: 891-909. 131 011 IHC; tested species: rat
Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.
Crèvecoeur J, Kaminski RM, Rogister B, Foerch P, Vandenplas C, Neveux M, Mazzuferi M, Kroonen J, Poulet C, Martin D, Sadzot B, et al.
Neuropathology and applied neurobiology (2014) 402: 191-204. 131 011 IHC; tested species: human
Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration.
Manca P, Mameli O, Caria MA, Torrejón-Escribano B, Blasi J
Neuroscience (2014) 266: 102-15. 131 011 WB, IHC
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.
Mendoza Schulz A, Jing Z, Sánchez Caro JM, Wetzel F, Dresbach T, Strenzke N, Wichmann C, Moser T
The EMBO journal (2014) 335: 512-27. 131 011 IHC
Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling.
Demyanenko GP, Mohan V, Zhang X, Brennaman LH, Dharbal KE, Tran TS, Manis PB, Maness PF
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3434: 11274-87. 131 011 IHC; tested species: mouse
Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord.
Horváth E, Woodhams SG, Nyilas R, Henstridge CM, Kano M, Sakimura K, Watanabe M, Katona I
The European journal of neuroscience (2014) 393: 419-34. 131 011 IHC; tested species: mouse
GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity.
Young SZ, Lafourcade CA, Platel JC, Lin TV, Bordey A
Frontiers in cellular neuroscience (2014) 8: 10. 131 011 IHC; tested species: mouse
Expression of voltage-gated calcium channel α(2)δ(4) subunits in the mouse and rat retina.
De Sevilla Müller LP, Liu J, Solomon A, Rodriguez A, Brecha NC
The Journal of comparative neurology (2013) 52111: 2486-501. 131 011 IHC; tested species: mouse
Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron.
Hioki H, Okamoto S, Konno M, Kameda H, Sohn J, Kuramoto E, Fujiyama F, Kaneko T
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 332: 544-55. 131 011 IHC
Remodelling of supraspinal neuroglial network in neuropathic pain is featured by a reactive gliosis of the nociceptive amygdala.
Marcello L, Cavaliere C, Colangelo AM, Bianco MR, Cirillo G, Alberghina L, Papa M
European journal of pain (London, England) (2013) 176: 799-810. 131 011 IHC; tested species: rat
ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice.
Antes R, Ezra-Elia R, Weinberger D, Solomon A, Ofri R, Michaelson DM
PloS one (2013) 85: e64949. 131 011 IHC
Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons.
Fan KY, Baufreton J, Surmeier DJ, Chan CS, Bevan MD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3240: 13718-28. 131 011 IHC, EM
Loss of cortical GABA terminals in Unverricht-Lundborg disease.
Buzzi A, Chikhladze M, Falcicchia C, Paradiso B, Lanza G, Soukupova M, Marti M, Morari M, Franceschetti S, Simonato M
Neurobiology of disease (2012) 472: 216-24. 131 011 IHC; tested species: mouse
Synaptotagmin-2 is a reliable marker for parvalbumin positive inhibitory boutons in the mouse visual cortex.
Sommeijer JP, Levelt CN
PloS one (2012) 74: e35323. 131 011 IHC; tested species: mouse
Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.
Seja P, Schonewille M, Spitzmaul G, Badura A, Klein I, Rudhard Y, Wisden W, Hübner CA, De Zeeuw CI, Jentsch TJ
The EMBO journal (2012) 315: 1217-30. 131 011 IHC; tested species: mouse
Cortactin-binding protein 2 modulates the mobility of cortactin and regulates dendritic spine formation and maintenance.
Chen YK, Hsueh YP
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 323: 1043-55. 131 011 IHC; tested species: mouse
Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn.
Polgár E, Sardella TC, Watanabe M, Todd AJ
The Journal of comparative neurology (2011) 5196: 1007-23. 131 011 IHC; tested species: rat
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia.
Chatzi C, Brade T, Duester G
PLoS biology (2011) 94: e1000609. 131 011 IHC; tested species: mouse
Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells.
Lee H, Brecha NC
The European journal of neuroscience (2010) 318: 1388-401. 131 011 IHC
Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers.
Micheva KD, Busse B, Weiler NC, O'Rourke N, Smith SJ
Neuron (2010) 684: 639-53. 131 011 IHC
Tomosyn expression pattern in the mouse hippocampus suggests both presynaptic and postsynaptic functions.
Barak B, Williams A, Bielopolski N, Gottfried I, Okun E, Brown MA, Matti U, Rettig J, Stuenkel EL, Ashery U
Frontiers in neuroanatomy (2010) 4: 149. 131 011 IHC; tested species: mouse
SV2 mediates entry of tetanus neurotoxin into central neurons.
Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER
PLoS pathogens (2010) 611: e1001207. 131 011 ICC, IHC; tested species: rat
Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters.
Bogen IL, Boulland JL, Mariussen E, Wright MS, Fonnum F, Kao HT, Walaas SI
Journal of neurochemistry (2006) 965: 1458-66. 131 011 IHC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.
Saito T, Iwata N, Tsubuki S, Takaki Y, Takano J, Huang SM, Suemoto T, Higuchi M, Saido TC
Nature medicine (2005) 114: 434-9. 131 011 IHC
Erythropoietin Stimulates GABAergic Maturation in the Mouse Hippocampus.
Khalid K, Frei J, Aboouf MA, Koester-Hegmann C, Gassmann M, Fritschy JM, Schneider Gasser EM
eNeuro () 81: . 131 011 IHC; tested species: mouse
Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neurons of the Adult Amygdala and Prefrontal Cortex.
Castillo-Gómez E, Pérez-Rando M, Bellés M, Gilabert-Juan J, Llorens JV, Carceller H, Bueno-Fernández C, García-Mompó C, Ripoll-Martínez B, Curto Y, Sebastiá-Ortega N, et al.
eNeuro () 42: . 131 011 IHC; tested species: mouse
Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles.
Li X, Qin L, Li Y, Yu H, Zhang Z, Tao C, Liu Y, Xue Y, Zhang X, Xu Z, Wang Y, et al.
Cell reports (2019) 284: 1015-1028.e5. 131 011 EM; tested species: rat
Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.
Fossati M, Assendorp N, Gemin O, Colasse S, Dingli F, Arras G, Loew D, Charrier C
Neuron (2019) : . 131 011 EM; tested species: mouse
Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons.
Fan KY, Baufreton J, Surmeier DJ, Chan CS, Bevan MD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3240: 13718-28. 131 011 IHC, EM
Critical Analysis of Particle Detection Artifacts in Synaptosome Flow Cytometry.
Hobson BD, Sims PA
eNeuro (2019) : . 131 011 FACS; tested species: mouse
Cat. No.: 131 011
Quantity: 100 µg
Price: $425.00
ErbB4 promotes inhibitory synapse formation by cell adhesion, independent of its kinase activity.
Luo B, Liu Z, Lin D, Chen W, Ren D, Yu Z, Xiong M, Zhao C, Fei E, Li B
Translational psychiatry (2021) 111: 361. 131 011 WB, ICC; tested species: mouse
A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome.
Cursano S, Battaglia CR, Urrutia-Ruiz C, Grabrucker S, Schön M, Bockmann J, Braumüller S, Radermacher P, Roselli F, Huber-Lang M, Boeckers TM, et al.
Molecular psychiatry (2020) : . 131 011 WB, IHC; tested species: mouse
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ, et al.
The EMBO journal (2020) : e103358. 131 011 WB; tested species: mouse
Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences.
Scheggi S, Guzzi F, Braccagni G, De Montis MG, Parenti M, Gambarana C
Molecular autism (2020) 111: 62. 131 011 WB; tested species: rat
A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment.
Li SM, Li B, Zhang L, Zhang GF, Sun J, Ji MH, Yang JJ
International immunopharmacology (2020) 87: 106814. 131 011 WB, IHC; tested species: mouse
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, et al.
Epilepsia (2020) : . 131 011 WB, IHC; tested species: mouse
Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain.
Chantranupong L, Saulnier JL, Wang W, Jones DR, Pacold ME, Sabatini BL
eLife (2020) 9: . 131 011 WB; tested species: mouse
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 131 011 WB, ICC; tested species: human
Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP.
Andrés-Benito P, Gelpi E, Povedano M, Santpere G, Ferrer I
Journal of neuropathology and experimental neurology (2018) : . 131 011 WB; tested species: human
Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
Chmielewska JJ, Kuzniewska B, Milek J, Urbanska K, Dziembowska M
Molecular neurobiology (2018) : . 131 011 WB; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks.
Vannini E, Restani L, Pietrasanta M, Panarese A, Mazzoni A, Rossetto O, Middei S, Micera S, Caleo M
Brain structure & function (2016) 2216: 2919-36. 131 011 WB
Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration.
Manca P, Mameli O, Caria MA, Torrejón-Escribano B, Blasi J
Neuroscience (2014) 266: 102-15. 131 011 WB, IHC
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses.
Zander JF, Münster-Wandowski A, Brunk I, Pahner I, Gómez-Lira G, Heinemann U, Gutiérrez R, Laube G, Ahnert-Hilger G
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 3022: 7634-45. 131 011 IP
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
ErbB4 promotes inhibitory synapse formation by cell adhesion, independent of its kinase activity.
Luo B, Liu Z, Lin D, Chen W, Ren D, Yu Z, Xiong M, Zhao C, Fei E, Li B
Translational psychiatry (2021) 111: 361. 131 011 WB, ICC; tested species: mouse
Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis.
Daura E, Tegelberg S, Yoshihara M, Jackson C, Simonetti F, Aksentjeff K, Ezer S, Hakala P, Katayama S, Kere J, Lehesjoki AE, et al.
Neurobiology of disease (2021) : 105418. 131 011 ICC; tested species: mouse
VAMP4 maintains a Ca2+-sensitive pool of spontaneously recycling synaptic vesicles.
Lin PY, Chanaday NL, Horvath PM, Ramirez DMO, Monteggia LM, Kavalali ET
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 131 011 ICC; tested species: rat
BDNF impact on synaptic dynamics: extra or intracellular long-term release differently regulates cultured hippocampal synapses.
Rauti R, Cellot G, D'Andrea P, Colliva A, Scaini D, Tongiorgi E, Ballerini L
Molecular brain (2020) 131: 43. 131 011 ICC; tested species: rat
Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment.
Pan-Vazquez A, Wefelmeyer W, Gonzalez Sabater V, Neves G, Burrone J
Neuron (2020) : . 131 011 ICC, IHC; tested species: mouse
Central Cholinergic Synapse Formation in Optimized Primary Septal-Hippocampal Co-cultures.
Djemil S, Ressel CR, Abdel-Ghani M, Schneeweis AK, Pak DTS
Cellular and molecular neurobiology (2020) : . 131 011 ICC; tested species: rat
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids.
Renner H, Grabos M, Becker KJ, Kagermeier TE, Wu J, Otto M, Peischard S, Zeuschner D, TsyTsyura Y, Disse P, Klingauf J, et al.
eLife (2020) 9: . 131 011 ICC; tested species: human
Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs. isogenic control.
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, Ambasudhan R, Talantova M, Lipton SA
eLife (2019) 8: . 131 011 WB, ICC; tested species: human
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 131 011 ICC; tested species: human
Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output.
Paraskevopoulou F, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3923: 4448-4460. 131 011 ICC; tested species: mouse
Differential Properties of the Synaptogenic Activities of the Neurexin Ligands Neuroligin1 and LRRTM2.
Dagar S, Gottmann K
Frontiers in molecular neuroscience (2019) 12: 269. 131 011 ICC; tested species: mouse
TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, et al.
Cell reports (2019) 295: 1130-1146.e8. 131 011 ICC; tested species: mouse
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, et al.
Science (New York, N.Y.) (2018) : . 131 011 ICC; tested species: rat
Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.
Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, et al.
Cell (2018) 1733: 735-748.e15. 131 011 ICC; tested species: mouse
MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells.
Tu J, Cao D, Li L, Cheung HH, Chan WY
FEBS open bio (2018) 84: 502-512. 131 011 ICC; tested species: human
Human iPSC-derived neuronal models for in vitro neurotoxicity assessment.
Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS
Neurotoxicology (2018) 67: 215-225. 131 011 ICC; tested species: human
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, et al.
Molecular systems biology (2018) 147: e8071. 131 011 ICC; tested species: mouse
The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice.
Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T
EBioMedicine (2018) : . 131 011 ICC; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan SK, Diaspro A, Del Bue A, Petrini EM, Barberis A, Cella Zanacchi F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 377: 1747-1756. 131 011 ICC
Inter-Synaptic Lateral Diffusion of GABAA Receptors Shapes Inhibitory Synaptic Currents.
de Luca E, Ravasenga T, Petrini EM, Polenghi A, Nieus T, Guazzi S, Barberis A
Neuron (2017) 951: 63-69.e5. 131 011 ICC; tested species: mouse
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.
Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, et al.
eLife (2017) 6: . 131 011 ICC; tested species: mouse
Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity.
Chacón PJ, del Marco Á, Arévalo Á, Domínguez-Giménez P, García-Segura LM, Rodríguez-Tébar A
Neurobiology of aging (2015) 362: 1057-71. 131 011 ICC, IHC
Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons.
Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ
Molecular brain (2015) 8: 10. 131 011 ICC
Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs.
Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME
Cell (2014) 1575: 1216-29. 131 011 ICC; tested species: mouse
Investigation of synapse formation and function in a glutamatergic-GABAergic two-neuron microcircuit.
Chang CL, Trimbuch T, Chao HT, Jordan JC, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 343: 855-68. 131 011 ICC; tested species: mouse
Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors.
Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I
The Journal of biological chemistry (2014) 28916: 11396-409. 131 011 ICC; tested species: rat
BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons.
Shinoda Y, Ahmed S, Ramachandran B, Bharat V, Brockelt D, Altas B, Dean C
Frontiers in synaptic neuroscience (2014) 6: 27. 131 011 ICC; tested species: rat
Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.
Murata Y, Constantine-Paton M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3311: 5040-52. 131 011 ICC; tested species: mouse,rat
Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons.
Hanson JE, Deng L, Hackos DH, Lo SC, Lauffer BE, Steiner P, Zhou Q
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3314: 5924-9. 131 011 ICC
Minimal Change in the cytoplasmic calcium dynamics in striatal GABAergic neurons of a DYT1 dystonia knock-in mouse model.
Iwabuchi S, Koh JY, Wang K, Ho KW, Harata NC
PloS one (2013) 811: e80793. 131 011 ICC
Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture.
Li H, Hader AT, Han YR, Wong JA, Babiarz J, Ricupero CL, Godfrey SB, Corradi JP, Fennell M, Hart RP, Plummer MR, et al.
Developmental neurobiology (2012) 726: 805-20. 131 011 ICC
Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex.
Takahashi H, Arstikaitis P, Prasad T, Bartlett TE, Wang YT, Murphy TH, Craig AM
Neuron (2011) 692: 287-303. 131 011 ICC; tested species: rat
SV2 mediates entry of tetanus neurotoxin into central neurons.
Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER
PLoS pathogens (2010) 611: e1001207. 131 011 ICC, IHC; tested species: rat
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, et al.
Journal of neurochemistry (2010) 1131: 153-65. 131 011 WB, IP, ICC
Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1.
McClelland AC, Sheffler-Collins SI, Kayser MS, Dalva MB
Proceedings of the National Academy of Sciences of the United States of America (2009) 10648: 20487-92. 131 011 ICC
PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering.
Baer K, Bürli T, Huh KH, Wiesner A, Erb-Vögtli S, Göckeritz-Dujmovic D, Moransard M, Nishimune A, Rees MI, Henley JM, Fritschy JM, et al.
Molecular and cellular neurosciences (2007) 352: 339-55. 131 011 ICC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Maternal Deprivation in Rats Decreases the Expression of Interneuron Markers in the Neocortex and Hippocampus.
Aksic M, Poleksic J, Aleksic D, Petronijevic N, Radonjic NV, Jakovcevski M, Kapor S, Divac N, Filipovic BR, Jakovcevski I
Frontiers in neuroanatomy (2021) 15: 670766. 131 011 IHC; tested species: rat
Early-life sevoflurane exposure impairs fear memory by suppressing extracellular signal-regulated kinase signaling in the bed nucleus of stria terminalis GABAergic neurons.
Zhao XP, Zhong F, Luo RY, Zhang YL, Luo C, Li H, Dai RP
Neuropharmacology (2021) 191: 108584. 131 011 IHC; tested species: mouse
Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration.
van Olst L, Rodriguez-Mogeda C, Picon C, Kiljan S, James RE, Kamermans A, van der Pol SMA, Knoop L, Michailidou I, Drost E, Franssen M, et al.
Acta neuropathologica (2021) 1416: 881-899. 131 011 IHC; tested species: rat
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice.
Frew J, Nygaard HB
Acta neuropathologica communications (2021) 91: 57. 131 011 IHC; tested species: mouse
Aberrant axo-axonic synaptic reorganization in the phosphorylated L1-CAM/calcium channel subunit alpha2 delta-1-containing central terminals of injured c-fibers in the spinal cord of a neuropathic pain model.
Yamanaka H, Okubo M, Kobayashi K, Noguchi K
eNeuro (2021) : . 131 011 IHC; tested species: rat
Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex.
Pintér A, Hevesi Z, Zahola P, Alpár A, Hanics J
Cellular signalling (2020) 74: 109710. 131 011 IHC; tested species: rat
Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment.
Pan-Vazquez A, Wefelmeyer W, Gonzalez Sabater V, Neves G, Burrone J
Neuron (2020) : . 131 011 ICC, IHC; tested species: mouse
Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain.
Lorenzo LE, Godin AG, Ferrini F, Bachand K, Plasencia-Fernandez I, Labrecque S, Girard AA, Boudreau D, Kianicka I, Gagnon M, Doyon N, et al.
Nature communications (2020) 111: 869. 131 011 IHC; tested species: rat
Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal.
Nuzzaci D, Cansell C, Liénard F, Nédélec E, Ben Fradj S, Castel J, Foppen E, Denis R, Grouselle D, Laderrière A, Lemoine A, et al.
Cell reports (2020) 309: 3067-3078.e5. 131 011 IHC; tested species: mouse
Rescue of PB-resistant neonatal seizures with single-dose of small-molecule TrkB antagonist show long-term benefits.
Kang SK, Ammanuel S, Adler DA, Kadam SD
Epilepsy research (2020) 159: 106249. 131 011 IHC; tested species: mouse
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation.
Ji MH, Lei L, Gao DP, Tong JH, Wang Y, Yang JJ
Brain, behavior, and immunity (2020) : . 131 011 IHC; tested species: rat
Microglial mTOR is neuronal protective and anti-epileptogenic in the pilocarpine model of temporal lobe epilepsy.
Zhao XF, Liao Y, Alam MM, Mathur R, Feustel P, Mazurkiewicz JE, Adamo MA, Zhu XC, Huang Y
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 131 011 IHC; tested species: mouse
A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment.
Li SM, Li B, Zhang L, Zhang GF, Sun J, Ji MH, Yang JJ
International immunopharmacology (2020) 87: 106814. 131 011 WB, IHC; tested species: mouse
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, et al.
Epilepsia (2020) : . 131 011 WB, IHC; tested species: mouse
The mouse olfactory peduncle 4: Development of synapses, perineuronal nets, and capillaries.
Collins LN, Brunjes PC
The Journal of comparative neurology (2020) 5284: 637-649. 131 011 IHC; tested species: mouse
Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.
Granger AJ, Wang W, Robertson K, El-Rifai M, Zanello AF, Bistrong K, Saunders A, Chow BW, Nuñez V, Turrero García M, Harwell CC, et al.
eLife (2020) 9: . 131 011 IHC; tested species: mouse
GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy.
Alhourani A, Fish KN, Wozny TA, Sudhakar V, Hamilton RL, Richardson RM
Journal of neurophysiology (2020) 1231: 392-406. 131 011 IHC; tested species: human
A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome.
Cursano S, Battaglia CR, Urrutia-Ruiz C, Grabrucker S, Schön M, Bockmann J, Braumüller S, Radermacher P, Roselli F, Huber-Lang M, Boeckers TM, et al.
Molecular psychiatry (2020) : . 131 011 WB, IHC; tested species: mouse
Synaptic regulation by OPRM1 variants in reward neurocircuitry.
Popova D, Desai N, Blendy JA, Pang ZP
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 131 011 IHC; tested species: mouse
ApoE4 Exacerbates Hippocampal Pathology Following Acute Brain Penetration Injury in Female Mice.
Ben-Moshe H, Luz I, Liraz O, Boehm-Cagan A, Salomon-Zimri S, Michaelson D
Journal of molecular neuroscience : MN (2019) : . 131 011 IHC; tested species: mouse
Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
Grove JCR, Hirano AA, de Los Santos J, McHugh CF, Purohit S, Field GD, Brecha NC, Barnes S
PLoS biology (2019) 174: e3000200. 131 011 IHC; KO verified; tested species: mouse
Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch.
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, Hor CC, Zaher N, Cin M, Slade H, Huang T, et al.
Neuron (2019) 1036: 1135-1149.e6. 131 011 IHC; tested species: mouse
The effects of early life stress on the excitatory/inhibitory balance of the medial prefrontal cortex.
Ohta KI, Suzuki S, Warita K, Sumitani K, Tenkumo C, Ozawa T, Ujihara H, Kusaka T, Miki T
Behavioural brain research (2019) : 112306. 131 011 IHC; tested species: rat
Variable colocalisation of GABAA receptor subunits and glycine receptors on neurons in the human hypoglossal nucleus.
Waldvogel HJ, Biggins FM, Singh A, Arasaratnam CJ, Faull RLM
Journal of chemical neuroanatomy (2019) 97: 99-111. 131 011 IHC; tested species: human
Proliferation of Inhibitory Input to the Substantia Nigra in Experimental Parkinsonism.
Faynveitz A, Lavian H, Jacob A, Korngreen A
Frontiers in cellular neuroscience (2019) 13: 417. 131 011 IHC; tested species: rat
Spinal motor circuit synaptic plasticity after peripheral nerve injury depends on microglia activation and a CCR2 mechanism.
Rotterman TM, Akhter ET, Lane AR, MacPherson KP, Garcia VV, Tansey MG, Alvarez FJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 131 011 IHC; tested species: mouse
Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation.
Andoh M, Shibata K, Okamoto K, Onodera J, Morishita K, Miura Y, Ikegaya Y, Koyama R
Cell reports (2019) 2710: 2817-2825.e5. 131 011 IHC; tested species: mouse
LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing.
Koebis M, Urata S, Shinoda Y, Okabe S, Yamasoba T, Nakao K, Aiba A, Furuichi T
Molecular brain (2019) 121: 20. 131 011 IHC; tested species: mouse
Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function.
Saito Y, Yuan Y, Zucker-Scharff I, Fak JJ, Jereb S, Tajima Y, Licatalosi DD, Darnell RB
Neuron (2019) 1014: 707-720.e5. 131 011 IHC; tested species: mouse
Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes.
Nam MH, Han KS, Lee J, Bae JY, An H, Park S, Oh SJ, Kim E, Hwang E, Bae YC, Lee CJ, et al.
Experimental neurobiology (2018) 272: 120-128. 131 011 IHC; tested species: mouse
Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Zhang B, Gokce O, Hale WD, Brose N, Südhof TC
The Journal of experimental medicine (2018) : . 131 011 IHC; tested species: mouse
Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood.
Tata B, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, et al.
Nature medicine (2018) : . 131 011 IHC; tested species: mouse
Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response.
Jhang J, Lee H, Kang MS, Lee HS, Park H, Han JH
Nature communications (2018) 91: 2744. 131 011 IHC; tested species: mouse
Dopamine receptors in the rat entopeduncular nucleus.
Lavian H, Loewenstern Y, Madar R, Almog M, Bar-Gad I, Okun E, Korngreen A
Brain structure & function (2018) : . 131 011 IHC; tested species: rat
Automated analysis of images for molecular quantification in immunohistochemistry.
Guirado R, Carceller H, Castillo-Gómez E, Castrén E, Nacher J
Heliyon (2018) 46: e00669. 131 011 IHC; tested species: mouse
Regulation of Synapse Development by Vgat Deletion from ErbB4-Positive Interneurons.
Lin TW, Tan Z, Barik A, Yin DM, Brudvik E, Wang H, Xiong WC, Mei L
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3810: 2533-2550. 131 011 IHC; KO verified; tested species: mouse
Input-specific synaptic location and function of the alpha5 GABAA receptor subunit in the mouse CA1 hippocampal neurons.
Magnin E, Francavilla R, Amalyan S, Gervais E, Suzanne David L, Luo X, Topolnik L
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 131 011 IHC; tested species: mouse
The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease-related pathology.
Bar R, Boehm-Cagan A, Luz I, Kleper-Wall Y, Michaelson DM
Alzheimer's & dementia (Amsterdam, Netherlands) (2018) 10: 1-11. 131 011 IHC; tested species: mouse
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434. 131 011 WB, ICC, IHC; tested species: rat
Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats.
Irintchev M, Guntinas-Lichius O, Irintchev A
Neural plasticity (2018) 2018: 7975013. 131 011 IHC; tested species: rat
Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy.
Li P, Fu X, Smith NA, Ziobro J, Curiel J, Tenga MJ, Martin B, Freedman S, Cea-Del Rio CA, Oboti L, Tsuchida TN, et al.
Neuron (2017) 962: 387-401.e6. 131 011 IHC; tested species: mouse
Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb.
Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K
The Journal of comparative neurology (2017) 5253: 574-591. 131 011 IHC; tested species: mouse
Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain.
Dunn AR, Hoffman CA, Stout KA, Ozawa M, Dhamsania RK, Miller GW
Brain research (2017) : . 131 011 IHC
Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis.
Nemes AD, Ayasoufi K, Ying Z, Zhou QG, Suh H, Najm IM
Scientific reports (2017) 71: 17702. 131 011 IHC; tested species: rat
Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy.
Farhan SMK, Nixon KCJ, Everest M, Edwards TN, Long S, Segal D, Knip MJ, Arts HH, Chakrabarti R, Wang J, Robinson JF, et al.
Human molecular genetics (2017) 2621: 4278-4289. 131 011 IHC; tested species: rat
Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia.
Rocco BR, Lewis DA, Fish KN
Biological psychiatry (2016) 7912: 1006-15. 131 011 IHC
LAMP5 Fine-Tunes GABAergic Synaptic Transmission in Defined Circuits of the Mouse Brain.
Tiveron MC, Beurrier C, Céni C, Andriambao N, Combes A, Koehl M, Maurice N, Gatti E, Abrous DN, Kerkerian-Le Goff L, Pierre P, et al.
PloS one (2016) 116: e0157052. 131 011 IHC
VGluT3-expressing CCK-positive basket cells construct invaginating synapses enriched with endocannabinoid signaling proteins in particular cortical and cortex-like amygdaloid regions of mouse brains.
Omiya Y, Uchigashima M, Konno K, Yamasaki M, Miyazaki T, Yoshida T, Kusumi I, Watanabe M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3510: 4215-28. 131 011 IHC; tested species: mouse
Cerebellar synaptogenesis is compromised in mouse models of DYT1 dystonia.
Vanni V, Puglisi F, Bonsi P, Ponterio G, Maltese M, Pisani A, Mandolesi G
Experimental neurology (2015) 271: 457-67. 131 011 IHC; tested species: mouse
Co-localization of glutamic acid decarboxylase and vesicular GABA transporter in cytochrome oxidase patches of macaque striate cortex.
Adams DL, Economides JR, Horton JC
Visual neuroscience (2015) 32: E026. 131 011 IHC
Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity.
Chacón PJ, del Marco Á, Arévalo Á, Domínguez-Giménez P, García-Segura LM, Rodríguez-Tébar A
Neurobiology of aging (2015) 362: 1057-71. 131 011 ICC, IHC
Structural and functional characterization of dendritic arbors and GABAergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala.
Klenowski PM, Fogarty MJ, Belmer A, Noakes PG, Bellingham MC, Bartlett SE
Journal of neurophysiology (2015) 1142: 942-57. 131 011 IHC
KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ
Nature communications (2015) 6: 6254. 131 011 IHC
A direct GABAergic output from the basal ganglia to frontal cortex.
Saunders A, Oldenburg IA, Berezovskii VK, Johnson CA, Kingery ND, Elliott HL, Xie T, Gerfen CR, Sabatini BL
Nature (2015) 5217550: 85-9. 131 011 IHC
Conditional targeting of medium spiny neurons in the striatal matrix.
Reinius B, Blunder M, Brett FM, Eriksson A, Patra K, Jonsson J, Jazin E, Kullander K
Frontiers in behavioral neuroscience (2015) 9: 71. 131 011 IHC
Reduced cholinergic and glutamatergic synaptic input to regenerated motoneurons after facial nerve repair in rats: potential implications for recovery of motor function.
Raslan A, Ernst P, Werle M, Thieme H, Szameit K, Finkensieper M, Guntinas-Lichius O, Irintchev A
Brain structure & function (2014) 2193: 891-909. 131 011 IHC; tested species: rat
Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.
Crèvecoeur J, Kaminski RM, Rogister B, Foerch P, Vandenplas C, Neveux M, Mazzuferi M, Kroonen J, Poulet C, Martin D, Sadzot B, et al.
Neuropathology and applied neurobiology (2014) 402: 191-204. 131 011 IHC; tested species: human
Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration.
Manca P, Mameli O, Caria MA, Torrejón-Escribano B, Blasi J
Neuroscience (2014) 266: 102-15. 131 011 WB, IHC
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.
Mendoza Schulz A, Jing Z, Sánchez Caro JM, Wetzel F, Dresbach T, Strenzke N, Wichmann C, Moser T
The EMBO journal (2014) 335: 512-27. 131 011 IHC
Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling.
Demyanenko GP, Mohan V, Zhang X, Brennaman LH, Dharbal KE, Tran TS, Manis PB, Maness PF
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3434: 11274-87. 131 011 IHC; tested species: mouse
Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord.
Horváth E, Woodhams SG, Nyilas R, Henstridge CM, Kano M, Sakimura K, Watanabe M, Katona I
The European journal of neuroscience (2014) 393: 419-34. 131 011 IHC; tested species: mouse
GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity.
Young SZ, Lafourcade CA, Platel JC, Lin TV, Bordey A
Frontiers in cellular neuroscience (2014) 8: 10. 131 011 IHC; tested species: mouse
Expression of voltage-gated calcium channel α(2)δ(4) subunits in the mouse and rat retina.
De Sevilla Müller LP, Liu J, Solomon A, Rodriguez A, Brecha NC
The Journal of comparative neurology (2013) 52111: 2486-501. 131 011 IHC; tested species: mouse
Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron.
Hioki H, Okamoto S, Konno M, Kameda H, Sohn J, Kuramoto E, Fujiyama F, Kaneko T
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 332: 544-55. 131 011 IHC
Remodelling of supraspinal neuroglial network in neuropathic pain is featured by a reactive gliosis of the nociceptive amygdala.
Marcello L, Cavaliere C, Colangelo AM, Bianco MR, Cirillo G, Alberghina L, Papa M
European journal of pain (London, England) (2013) 176: 799-810. 131 011 IHC; tested species: rat
ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice.
Antes R, Ezra-Elia R, Weinberger D, Solomon A, Ofri R, Michaelson DM
PloS one (2013) 85: e64949. 131 011 IHC
Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons.
Fan KY, Baufreton J, Surmeier DJ, Chan CS, Bevan MD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3240: 13718-28. 131 011 IHC, EM
Loss of cortical GABA terminals in Unverricht-Lundborg disease.
Buzzi A, Chikhladze M, Falcicchia C, Paradiso B, Lanza G, Soukupova M, Marti M, Morari M, Franceschetti S, Simonato M
Neurobiology of disease (2012) 472: 216-24. 131 011 IHC; tested species: mouse
Synaptotagmin-2 is a reliable marker for parvalbumin positive inhibitory boutons in the mouse visual cortex.
Sommeijer JP, Levelt CN
PloS one (2012) 74: e35323. 131 011 IHC; tested species: mouse
Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.
Seja P, Schonewille M, Spitzmaul G, Badura A, Klein I, Rudhard Y, Wisden W, Hübner CA, De Zeeuw CI, Jentsch TJ
The EMBO journal (2012) 315: 1217-30. 131 011 IHC; tested species: mouse
Cortactin-binding protein 2 modulates the mobility of cortactin and regulates dendritic spine formation and maintenance.
Chen YK, Hsueh YP
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 323: 1043-55. 131 011 IHC; tested species: mouse
Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn.
Polgár E, Sardella TC, Watanabe M, Todd AJ
The Journal of comparative neurology (2011) 5196: 1007-23. 131 011 IHC; tested species: rat
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia.
Chatzi C, Brade T, Duester G
PLoS biology (2011) 94: e1000609. 131 011 IHC; tested species: mouse
Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells.
Lee H, Brecha NC
The European journal of neuroscience (2010) 318: 1388-401. 131 011 IHC
Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers.
Micheva KD, Busse B, Weiler NC, O'Rourke N, Smith SJ
Neuron (2010) 684: 639-53. 131 011 IHC
Tomosyn expression pattern in the mouse hippocampus suggests both presynaptic and postsynaptic functions.
Barak B, Williams A, Bielopolski N, Gottfried I, Okun E, Brown MA, Matti U, Rettig J, Stuenkel EL, Ashery U
Frontiers in neuroanatomy (2010) 4: 149. 131 011 IHC; tested species: mouse
SV2 mediates entry of tetanus neurotoxin into central neurons.
Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER
PLoS pathogens (2010) 611: e1001207. 131 011 ICC, IHC; tested species: rat
Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters.
Bogen IL, Boulland JL, Mariussen E, Wright MS, Fonnum F, Kao HT, Walaas SI
Journal of neurochemistry (2006) 965: 1458-66. 131 011 IHC
Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7826-38. 131 011 WB, ICC, IHC
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.
Saito T, Iwata N, Tsubuki S, Takaki Y, Takano J, Huang SM, Suemoto T, Higuchi M, Saido TC
Nature medicine (2005) 114: 434-9. 131 011 IHC
Erythropoietin Stimulates GABAergic Maturation in the Mouse Hippocampus.
Khalid K, Frei J, Aboouf MA, Koester-Hegmann C, Gassmann M, Fritschy JM, Schneider Gasser EM
eNeuro () 81: . 131 011 IHC; tested species: mouse
Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neurons of the Adult Amygdala and Prefrontal Cortex.
Castillo-Gómez E, Pérez-Rando M, Bellés M, Gilabert-Juan J, Llorens JV, Carceller H, Bueno-Fernández C, García-Mompó C, Ripoll-Martínez B, Curto Y, Sebastiá-Ortega N, et al.
eNeuro () 42: . 131 011 IHC; tested species: mouse
Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles.
Li X, Qin L, Li Y, Yu H, Zhang Z, Tao C, Liu Y, Xue Y, Zhang X, Xu Z, Wang Y, et al.
Cell reports (2019) 284: 1015-1028.e5. 131 011 EM; tested species: rat
Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.
Fossati M, Assendorp N, Gemin O, Colasse S, Dingli F, Arras G, Loew D, Charrier C
Neuron (2019) : . 131 011 EM; tested species: mouse
Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons.
Fan KY, Baufreton J, Surmeier DJ, Chan CS, Bevan MD
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3240: 13718-28. 131 011 IHC, EM
Critical Analysis of Particle Detection Artifacts in Synaptosome Flow Cytometry.
Hobson BD, Sims PA
eNeuro (2019) : . 131 011 FACS; tested species: mouse
Background
The vesicular GABA transporter VGAT is responsible for uptake and storage of GABA and glycine by synaptic vesicles in the central nervous system. For this reason it is frequently referred to as the vesicular inhibitory aminoacid transporter VIAAT. It is different from the plasma membrane transporters in that it is driven by a proton electrochemical gradient across the vesicle membrane. So far, only one isoform is known. VGAT is currently the best marker for inhibitory nerve terminals.