Tailor-made Antibodies
and Tools for Life Science

Synapsin1/2 antibody - 106 003 K.O.

Synapsins are peripheral synaptic vesicle proteins and substrate for several protein kinases
Rabbit polyclonal purified antibody
Cat. No.: 106 003
Amount: 50 µg
Price: $460.00
Cat. No. 106 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
DNA-PAINT: yes (see remarks)
Clarity: 1 : 200 (see remarks)
ELISA: yes (see remarks)
Immunogen Synthetic peptide corresponding to AA 2 to 28 from rat Synapsin1 (UniProt Id: P09951)
Reactivity Reacts with: human (P17600, Q92777), rat (P09951, Q63537), mouse (O88935, Q64332), hamster, cow, zebrafish.
Other species not tested yet.
Specificity Specific for synapsins 1a/b and 2a/b. K.O. validated
Matching control protein/peptide 106-0P
Remarks

DNA-PAINT: This antibody has been successfully used for DNA-PAINT application (see Unterauer et al., 2024; PMID: 38552614).
Clarity: This antibody has been successfully used for CLARITY application in human brain (Woelfle et al., 2023; PMID: 37221592).
ELISA: Suitable as detector antibody for sandwich-ELISA with cat. no. 106 011 as capture antibody. The ELISA-protocol for membrane proteins is recommended.

Data sheet 106_003.pdf

References for Synapsin1/2 - 106 003

A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome.
Cursano S, Battaglia CR, Urrutia-Ruiz C, Grabrucker S, Schön M, Bockmann J, Braumüller S, Radermacher P, Roselli F, Huber-Lang M, Boeckers TM, et al.
Molecular psychiatry (2020) : . 106 003 WB; tested species: mouse
Cat. No.: 106 003
Amount: 50 µg
Price: $460.00