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Synaptoporin peptide - 102-0P

Synaptoporin s a synaptic vesicle membrane protein similar to synaptophysin1 enriched in Mossy fibres
control peptide
Cat. No.: 102-0P
Amount: 100 µg
Price: $105.00
Cat. No. 102-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Applications
 
Immunogen Synthetic peptide corresponding to AA 250 to 265 from rat Synaptoporin (UniProt Id: P22831)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 102 005, 101 111
Remarks

This control peptide consists of the synthetic peptide (EFGQQPSGPTSFNN) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 102-0p.pdf
Cat. No.: 102-0P
Amount: 100 µg
Price: $105.00
Background

Synaptoporin, also known as synaptophysin 2 and p38-2, is highly homologous to synaptophysin 1 but encoded by a different gene. Like synaptopysin 1, synaptoporin contains four transmembrane regions and a short cytoplasmic tail. Unlike synaptophysin 1, it is not glycosylated.
The distributions of synaptophysin 1 and synaptoporin are different. Synaptophysin 1 is more uniformly expressed whereas synaptoporin is particularly enriched in mossy fiber synapses in the hippocampus. It is thus an excellent marker for subsets of synapses.

Protocols