Cat. No.: 103 302
Amount: 200 µl
Price:
$355.00
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| Cat. No. 103 302 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 216 to 229 from mouse Synaptogyrin3 (UniProt Id: Q8R191) |
| Reactivity |
Reacts with: mouse (Q8R191). Other species not tested yet. No signal on rat Synaptogyrin 3 (D4ABK1). Detects rat Synaptogyrin 3 isoform X1 (XP_006246009.2) |
| Specificity | K.O. validated PubMed: 31090538 |
| Matching control protein/peptide | 103-3P |
| Data sheet | 103_302.pdf |
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Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (synaptogyrin 1 and 3) and one ubiquitous, synaptogyrin 2 or cellugyrin isoform.
Synaptogyrins are integral membrane proteins and localize to the membrane of small vesicles. Synaptogyrin 1 and 3 are expressed in the brain whereby the latter shows a more restricted expression pattern with high levels in the mossy fiber region of the hippocampus, substantia nigra pars reticulata, pallidum, and deep cerebellar nuclei.
Synaptogyrin 2/cellugyrin, a close relative, is expressed in all tissues, for instance, in distinct populations of GLUT 4 containing vesicles.