Cat. No.: 316 003
Amount: 50 µg
Price:
$375.00
Cat. No. 316 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications |
Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IP: not tested yet Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: not recommended Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: not tested yet Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.', $event)" style="cursor: help;">IHC-P: not tested yet |
Immunogen | Recombinant protein corresponding to AA 1 to 335 from mouse RIM-BP1 (UniProt Id: Q7TNF8) |
Reactivity |
Reacts with: rat (Q9JIR0), mouse (Q7TNF8). Other species not tested yet. |
Specificity | K.O. validated PubMed: 27537484 |
Data sheet | 316_003.pdf |
RIM-BP 1, the benzodiazepine receptor associated protein 1 (BZRAP 1), and RIM-BP 2 have been identified as RIM interaction partner and are supposed to form the active zone core complex with RIM, Munc-13, liprin-α and ELKs.
Like RIM and Munc-13, RIM-BPs are multidomain proteins composed of a string of identifiable modules like SH3 or fibronectin type III repeats. Several splice variants for RIM-BPs have been described. .