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Home > Products > 129 013

Neuroligin1 antibody cytoplasmic domain - 129 013 K.O.

Neuroligins are postsynaptic cell adhesion molecules
Rabbit polyclonal purified antibody
Cat. No.: 129 013
Amount: 50 µg
Price: $375.00
Cat. No. 129 013 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 737 to 754 from mouse Neuroligin1 (UniProt Id: Q99K10)
Reactivity Reacts with: rat (Q62765), mouse (Q99K10).
Other species not tested yet.
Specificity K.O. validated
Data sheet 129_013.pdf

References for Neuroligin1 - 129 013

Cortical reorganization of the glutamate synapse in the activity-based anorexia rat model: Impact on cognition.
Mottarlini F, Targa G, Bottan G, Tarenzi B, Fumagalli F, Caffino L
Journal of neurochemistry (2022) 1614: 350-365. 129 013 WB; tested species: rat
Responsivity of serotonin transporter knockout rats to short and long access to cocaine: Modulation of the glutamate signalling in the nucleus accumbens shell.
Caffino L, Mottarlini F, Targa G, Verheij MMM, Fumagalli F, Homberg JR
British journal of pharmacology (2022) 17914: 3727-3739. 129 013 WB; tested species: rat
Hevin-calcyon interaction promotes synaptic reorganization after brain injury.
Kim JH, Jung HG, Kim A, Shim HS, Hyeon SJ, Lee YS, Han J, Jung JH, Lee J, Ryu H, Park JY, et al.
Cell death and differentiation (2021) 289: 2571-2588. 129 013 WB; tested species: mouse
A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency.
Mastro TL, Preza A, Basu S, Chattarji S, Till SM, Kind PC, Kennedy MB
eLife (2020) 9: . 129 013 WB; tested species: rat
Prefrontal Nectin3 Reduction Mediates Adolescent Stress-Induced Deficits of Social Memory, Spatial Working Memory, and Dendritic Structure in Mice.
Wang HL, Li JT, Wang H, Sun YX, Liu R, Wang XD, Su YA, Si TM
Neuroscience bulletin (2020) : . 129 013 WB; tested species: mouse
Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation.
Letellier M, Lagardère M, Tessier B, Janovjak H, Thoumine O
eLife (2020) 9: . 129 013 WB, IP; tested species: mouse
TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, et al.
Cell reports (2019) 295: 1130-1146.e8. 129 013 WB; tested species: mouse
Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.
Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, Leung C, Pak D, Jia Z, Xie W
The Journal of cell biology (2016) 2124: 449-63. 129 013 WB; tested species: mouse
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D
Cell reports (2015) 118: 1176-83. 129 013 WB; KD verified; tested species: rat
Promoter-like sequences regulating transcriptional activity in neurexin and neuroligin genes.
Runkel F, Rohlmann A, Reissner C, Brand SM, Missler M
Journal of neurochemistry (2013) 1271: 36-47. 129 013 WB
Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation.
Letellier M, Lagardère M, Tessier B, Janovjak H, Thoumine O
eLife (2020) 9: . 129 013 WB, IP; tested species: mouse
Cat. No.: 129 013
Amount: 50 µg
Price: $375.00
Cortical reorganization of the glutamate synapse in the activity-based anorexia rat model: Impact on cognition.
Mottarlini F, Targa G, Bottan G, Tarenzi B, Fumagalli F, Caffino L
Journal of neurochemistry (2022) 1614: 350-365. 129 013 WB; tested species: rat
Responsivity of serotonin transporter knockout rats to short and long access to cocaine: Modulation of the glutamate signalling in the nucleus accumbens shell.
Caffino L, Mottarlini F, Targa G, Verheij MMM, Fumagalli F, Homberg JR
British journal of pharmacology (2022) 17914: 3727-3739. 129 013 WB; tested species: rat
Hevin-calcyon interaction promotes synaptic reorganization after brain injury.
Kim JH, Jung HG, Kim A, Shim HS, Hyeon SJ, Lee YS, Han J, Jung JH, Lee J, Ryu H, Park JY, et al.
Cell death and differentiation (2021) 289: 2571-2588. 129 013 WB; tested species: mouse
A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency.
Mastro TL, Preza A, Basu S, Chattarji S, Till SM, Kind PC, Kennedy MB
eLife (2020) 9: . 129 013 WB; tested species: rat
Prefrontal Nectin3 Reduction Mediates Adolescent Stress-Induced Deficits of Social Memory, Spatial Working Memory, and Dendritic Structure in Mice.
Wang HL, Li JT, Wang H, Sun YX, Liu R, Wang XD, Su YA, Si TM
Neuroscience bulletin (2020) : . 129 013 WB; tested species: mouse
Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation.
Letellier M, Lagardère M, Tessier B, Janovjak H, Thoumine O
eLife (2020) 9: . 129 013 WB, IP; tested species: mouse
TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, et al.
Cell reports (2019) 295: 1130-1146.e8. 129 013 WB; tested species: mouse
Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.
Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, Leung C, Pak D, Jia Z, Xie W
The Journal of cell biology (2016) 2124: 449-63. 129 013 WB; tested species: mouse
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D
Cell reports (2015) 118: 1176-83. 129 013 WB; KD verified; tested species: rat
Promoter-like sequences regulating transcriptional activity in neurexin and neuroligin genes.
Runkel F, Rohlmann A, Reissner C, Brand SM, Missler M
Journal of neurochemistry (2013) 1271: 36-47. 129 013 WB
Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation.
Letellier M, Lagardère M, Tessier B, Janovjak H, Thoumine O
eLife (2020) 9: . 129 013 WB, IP; tested species: mouse
WB
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin1 and neuroligin3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin2 is found exclusively on inhibitory synapses.
Mutations in neuroligin3 and neuroligin4 have been implicated with a rare, heritable form of autism.
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