Cat. No.: 405 003
Amount: 50 µg
Price:
$375.00
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| Cat. No. 405 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 1 to 658 from rat HDC (UniProt Id: P16453) |
| Reactivity |
Reacts with: mouse (P23738), rat (P16453). Other species not tested yet. |
| Data sheet | 405_003.pdf |
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Histamine is synthesized by histidine decarboxylase (HDC) in many different cell types. Mast cells and basopile granulocytes store histamine in their granules that is released upon external stimulation.
In addition histamine acts as a modulatory neurotransmitter in the mammalian brain.
HDC expressing neurons occur in the tuberomammillary nucleus (TMN), which is located in the hypothalamus. It is the only site of neuronal histamine synthesis in the adult mammalian brain.