Low-frequency RTMS attenuates social impairment in the VPA-induced mouse model.Wang X, Li Y, Li R, Yuan L, Hua Y, Cai Y, Liu X
Behavioural brain research (2024) 472: 115156.
147 111 WB; tested species: mouse
Effects of psoralidin on the expression of glutamate decarboxylases and inhibitory synapse development.Lee SE, Lee GH
Journal of Asian natural products research (2024) : 1-9.
147 111 WB; tested species: mouse
Glycine Receptor β-Targeting Autoantibodies Contribute to the Pathology of Autoimmune Diseases.Wiessler AL, Talucci I, Piro I, Seefried S, Hörlin V, Baykan BB, Tüzün E, Schaefer N, Maric HM, Sommer C, Villmann C, et al.
Neurology(R) neuroimmunology & neuroinflammation (2024) 112: e200187.
147 111 WB, ICC; tested species: human,mouse
Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation.Rauschenberger V, Piro I, Kasaragod VB, Hörlin V, Eckes AL, Kluck CJ, Schindelin H, Meinck HM, Wickel J, Geis C, Tüzün E, et al.
Frontiers in molecular neuroscience (2023) 16: 1089101.
147 111 WB; tested species: human
Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice.Chou MY, Cao X, Hou KC, Tsai MH, Lee CY, Kuo MF, Wu VC, Huang HY, Akbarian S, Chang SK, Hu CY, et al.
Communications biology (2023) 61: 267.
147 111 WB; tested species: mouse
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.Wen L, Yang X, Wu Z, Fu S, Zhan Y, Chen Z, Bi D, Shen Y
Cell reports (2023) 424: 112349.
147 111 WB, IHC; tested species: mouse
Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus.Lin PY, Chen LY, Jiang M, Trotter JH, Seigneur E, Südhof TC
Science advances (2023) 91: eadd8856.
147 111 WB; tested species: mouse
RNA supply drives physiological granule assembly in neurons.Bauer KE, Bargenda N, Schieweck R, Illig C, Segura I, Harner M, Kiebler MA
Nature communications (2022) 131: 2781.
147 111 WB; tested species: rat
Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia.Cramer T, Gill R, Thirouin ZS, Vaas M, Sampath S, Martineau F, Noya SB, Panzanelli P, Sudharshan TJJ, Colameo D, Chang PK, et al.
Science advances (2022) 89: eabj0112.
147 111 WB, IHC; tested species: mouse
Acute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder.Iezzi D, Curti L, Ranieri G, Gerace E, Costa A, Ilari A, La Rocca A, Luceri C, D'Ambrosio M, Silvestri L, Scardigli M, et al.
Pharmacological research (2022) 183: 106401.
147 111 WB; tested species: rat
Hippocampal parvalbumin interneurons play a critical role in memory development.Miranda JM, Cruz E, Bessières B, Alberini CM
Cell reports (2022) 417: 111643.
147 111 WB; tested species: rat
Increasing the interval between repeated anesthetic exposures reduces long-lasting synaptic changes in late post-natal mice.Ju X, Cui J, Lee Y, Park S, Hong B, Yoo S, Kim YH, Ko Y, Lim C, Lee SY, Kweon GR, et al.
Journal of neurochemistry (2021) 1561: 76-87.
147 111 WB; tested species: mouse
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice.Prieto M, Folci A, Poupon G, Schiavi S, Buzzelli V, Pronot M, François U, Pousinha P, Lattuada N, Abelanet S, Castagnola S, et al.
Nature communications (2021) 121: 1557.
147 111 WB; tested species: mouse
Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.Yoshida T, Yamagata A, Imai A, Kim J, Izumi H, Nakashima S, Shiroshima T, Maeda A, Iwasawa-Okamoto S, Azechi K, Osaka F, et al.
Nature communications (2021) 121: 1848.
147 111 WB; tested species: mouse
Pumilio2 and Staufen2 selectively balance the synaptic proteome.Schieweck R, Riedemann T, Forné I, Harner M, Bauer KE, Rieger D, Ang FY, Hutten S, Demleitner AF, Popper B, Derdak S, et al.
Cell reports (2021) 3512: 109279.
147 111 WB; tested species: mouse
Novel Functional Properties of Missense Mutations in the Glycine Receptor β Subunit in Startle Disease.Piro I, Eckes AL, Kasaragod VB, Sommer C, Harvey RJ, Schaefer N, Villmann C
Frontiers in molecular neuroscience (2021) 14: 745275.
147 111 WB, ICC; tested species: mouse
Spinal Cord Neuronal Network Formation in a 3D Printed Reinforced Matrix-A Model System to Study Disease Mechanisms.Fischhaber N, Faber J, Bakirci E, Dalton PD, Budday S, Villmann C, Schaefer N
Advanced healthcare materials (2021) 1019: e2100830.
147 111 WB, ICC, UPTAKE
Neuroligin-3 Regulates Excitatory Synaptic Transmission and EPSP-Spike Coupling in the Dentate Gyrus In Vivo.Muellerleile J, Vnencak M, Ippolito A, Krueger-Burg D, Jungenitz T, Schwarzacher SW, Jedlicka P
Molecular neurobiology (2021) : .
147 111 WB; tested species: mouse
Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity.Garcia JD, Gookin SE, Crosby KC, Schwartz SL, Tiemeier E, Kennedy MJ, Dell'Acqua ML, Herson PS, Quillinan N, Smith KR
Cell reports (2021) 3712: 110142.
147 111 WB, ICC; tested species: rat
Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.Gonatopoulos-Pournatzis T, Niibori R, Salter EW, Weatheritt RJ, Tsang B, Farhangmehr S, Liang X, Braunschweig U, Roth J, Zhang S, Henderson T, et al.
Molecular cell (2020) : .
147 111 WB; tested species: mouse
Phosphorylation on Ser 359 of the α2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses.Nakamura Y, Morrow DH, Nathanson AJ, Henley JM, Wilkinson KA, Moss SJ
The Journal of biological chemistry (2020) : .
147 111 WB; tested species: rat
Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation.Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR
Cell reports (2020) 3112: 107785.
147 111 WB; tested species: rat
Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses.Han KA, Lee HY, Lim D, Shin J, Yoon TH, Liu X, Um JW, Choi SY, Ko J
Molecular brain (2020) 131: 94.
147 111 WB, ICC; tested species: mouse
A Role for mir-26a in Stress: A Potential sEV Biomarker and Modulator of Excitatory Neurotransmission.Lafourcade CA, Fernández A, Ramírez JP, Corvalán K, Carrasco MÁ, Iturriaga A, Bátiz LF, Luarte A, Wyneken U
Cells (2020) 96: .
147 111 WB; tested species: rat
Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways.Kim H, Kim D, Kim J, Lee HY, Park D, Kang H, Matsuda K, Sterky FH, Yuzaki M, Kim JY, Choi SY, et al.
The Journal of biological chemistry (2020) : .
147 111 WB; tested species: mouse
Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes.Poston RG, Murphy L, Rejepova A, Ghaninejad-Esfahani M, Segales J, Mulligan K, Saha RN
The Journal of biological chemistry (2020) : .
147 111 WB; tested species: rat
The small GTPase ARF6 regulates GABAergic synapse development.Kim H, Jung H, Jung H, Kwon SK, Ko J, Um JW
Molecular brain (2020) 131: 2.
147 111 WB, ICC; tested species: rat
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, et al.
Neuron (2019) : .
147 111 WB; tested species: mouse
CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice.Petrov AM, Lam M, Mast N, Moon J, Li Y, Maxfield E, Pikuleva IA
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2019) : .
147 111 WB; tested species: mouse
Developmental changes in plasticity, synaptic, glia, and connectivity protein levels in rat basolateral amygdala.Bessières B, Jia M, Travaglia A, Alberini CM
Learning & memory (Cold Spring Harbor, N.Y.) (2019) 2611: 436-448.
147 111 WB; tested species: rat
UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism.Trobiani L, Favaloro FL, Di Castro MA, Di Mattia M, Cariello M, Miranda E, Canterini S, De Stefano ME, Comoletti D, Limatola C, De Jaco A, et al.
Neurobiology of disease (2018) : .
147 111 WB; tested species: mouse
Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response.Li Y, Kim R, Cho YS, Song WS, Kim D, Kim K, Roh JD, Chung C, Park H, Yang E, Kim SJ, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3826: 5872-5887.
147 111 WB; tested species: mouse
Developmental changes in plasticity, synaptic, glia, and connectivity protein levels in rat medial prefrontal cortex.Jia M, Travaglia A, Pollonini G, Fedele G, Alberini CM
Learning & memory (Cold Spring Harbor, N.Y.) (2018) 2510: 533-543.
147 111 WB; tested species: rat
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Do Heo W, Kim DW, Yeo CY, Kim CH, Liu QS, et al.
Nature communications (2018) 91: 3434.
147 111 WB; tested species: rat
Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.Chmielewska JJ, Kuzniewska B, Milek J, Urbanska K, Dziembowska M
Molecular neurobiology (2018) : .
147 111 WB; tested species: mouse
S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, Santamaria-Araujo JA, Winkelmann A, Ayton S, Bush AI, Kloppenburg P, et al.
The Journal of clinical investigation (2017) 12712: 4365-4378.
147 111 WB, ICC; tested species: mouse
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.Li J, Casteels T, Frogne T, Ingvorsen C, Honoré C, Courtney M, Huber KVM, Schmitner N, Kimmel RA, Romanov RA, Sturtzel C, et al.
Cell (2017) 1681-2: 86-100.e15.
147 111 WB
Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses.Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, Deeb TZ, Srivastava DP, Tyagarajan SK, Pangalos MN, Triller A, Maguire J, Brandon NJ, Moss SJ, et al.
Proceedings of the National Academy of Sciences of the United States of America (2017) 11444: 11763-11768.
147 111 ICC, WB
Cadherin-10 Maintains Excitatory/Inhibitory Ratio through Interactions with Synaptic Proteins.Smith KR, Jones KA, Kopeikina KJ, Burette AC, Copits BA, Yoon S, Forrest MP, Fawcett-Patel JM, Hanley JG, Weinberg RJ, Swanson GT, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3746: 11127-11139.
147 111 WB; tested species: rat
Analysis of SUMO1-conjugation at synapses.Daniel JA, Cooper BH, Palvimo JJ, Zhang FP, Brose N, Tirard M
eLife (2017) 6: .
147 111 WB; tested species: mouse
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.Tanabe Y, Naito Y, Vasuta C, Lee AK, Soumounou Y, Linhoff MW, Takahashi H
Nature communications (2017) 81: 408.
147 111 WB
Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission.Ghosh H, Auguadri L, Battaglia S, Simone Thirouin Z, Zemoura K, Messner S, Acuña MA, Wildner H, Yévenes GE, Dieter A, Kawasaki H, et al.
Nature communications (2016) 7: 13365.
147 111 IP, WB
Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice.O'Sullivan GA, Jedlicka P, Chen HX, Kalbouneh H, Ippolito A, Deller T, Nawrotzki RA, Kuhse J, Kalaidzidis YL, Kirsch J, Schwarzacher SW, et al.
Molecular and cellular neurosciences (2016) 72: 101-13.
147 111 WB; KO verified
An E3-ligase-based method for ablating inhibitory synapses.Gross GG, Straub C, Perez-Sanchez J, Dempsey WP, Junge JA, Roberts RW, Trinh le A, Fraser SE, De Koninck Y, De Koninck P, Sabatini BL, et al.
Nature methods (2016) 138: 673-8.
147 111 WB, ICC; tested species: mouse,zebrafish
Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation.Flores CE, Nikonenko I, Mendez P, Fritschy JM, Tyagarajan SK, Muller D
Proceedings of the National Academy of Sciences of the United States of America (2015) 1121: E65-72.
147 111 WB
Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo.Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW
Brain structure & function (2015) 2201: 47-58.
147 111 WB
Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.Hoy JL, Haeger PA, Constable JR, Arias RJ, McCallum R, Kyweriga M, Davis L, Schnell E, Wehr M, Castillo PE, Washbourne P, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3322: 9364-84.
147 111 WB; tested species: mouse
Target-derived matricryptins organize cerebellar synapse formation through α3β1 integrins.Su J, Stenbjorn RS, Gorse K, Su K, Hauser KF, Ricard-Blum S, Pihlajaniemi T, Fox MA
Cell reports (2012) 22: 223-30.
147 111 WB; tested species: mouse
Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures.Varley ZK, Pizzarelli R, Antonelli R, Stancheva SH, Kneussel M, Cherubini E, Zacchi P
The Journal of biological chemistry (2011) 28623: 20942-51.
147 111 WB
Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.Hoon M, Soykan T, Falkenburger B, Hammer M, Patrizi A, Schmidt KF, Sassoè-Pognetto M, Löwel S, Moser T, Taschenberger H, Brose N, et al.
Proceedings of the National Academy of Sciences of the United States of America (2011) 1087: 3053-8.
147 111 WB, IHC
Differential localization of gamma-aminobutyric acid type A and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: an immunohistochemical study.Waldvogel HJ, Baer K, Eady E, Allen KL, Gilbert RT, Mohler H, Rees MI, Nicholson LF, Faull RL
The Journal of comparative neurology (2010) 5183: 305-28.
147 111 WB, IHC; tested species: human
Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.Förstera B, Belaidi AA, Jüttner R, Bernert C, Tsokos M, Lehmann TN, Horn P, Dehnicke C, Schwarz G, Meier JC
Brain : a journal of neurology (2010) 133Pt 12: 3778-94.
147 111 WB
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC
Science (New York, N.Y.) (2010) 3295999: 1663-7.
147 111 WB
Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis.Smolinsky B, Eichler SA, Buchmeier S, Meier JC, Schwarz G
The Journal of biological chemistry (2008) 28325: 17370-9.
147 111 WB
Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex.Koga K, Shimoyama S, Yamada A, Furukawa T, Nikaido Y, Furue H, Nakamura K, Ueno S
Molecular pain () 14: 1744806918783478.
147 111 WB; tested species: mouse