Cat. No.: 375-0P
Amount: 100 µg
Price:
$105.00
|
|
|
| Cat. No. 375-0P |
100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized! |
| Applications |
IP: N/A ICC: N/A IHC: N/A IHC-P: N/A |
| Immunogen | Synthetic peptide corresponding to AA 1159 to 1169 from mouse CD11c (UniProt Id: Q9QXH4) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Matching antibodies | HS-375 003, HS-375 004 |
| Remarks |
This control peptide consists of the synthetic peptide (aa 1159 - 1169 of mouse CD 11c) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 375-0p.pdf |
Important information|
|
CD11c or Integrin alpha-X (ITGAX) is a heterodimeric glycoprotein consisting of an α- and β-subunit and has seven repeating integrin domains. This transmembrane receptor type I plays a pivotal role in T cell killing and mediates intercellular adhesions during inflammation. Predominat expression levels have been found in dendritic cells, monocytes, macrophages, neutrophils and a small subset of B cells. Under pathological conditions, CD11c is a marker for hairy cell leukemia, acute non-lymphocytic leukemias, and some chronic lymphocytic leukemias.