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CD11c antibody - HS-375 003

CD11c is a fibrinogen receptor involved in cell-cell interaction during inflammation
Polyclonal rabbit purified antibody
Cat. No.: HS-375 003
Amount: 200 µl
Price: $370.00
Cat. No. HS-375 003 200 µl specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C to -80°C until use.
Applications IHC: 1 : 100 (see remarks) gallery  
IHC-P/FFPE: 1 : 100 gallery  
Immunogen Synthetic peptide corresponding to AA 1159 to 1169 from mouse CD11c (UniProt Id: Q9QXH4)
Reactivity Reacts with: mouse (Q9QXH4).
No signal: rat, human (P20702).
Other species not tested yet.
Specificity Specific for CD11c.
Matching control protein/peptide 375-0P
Remarks

IHC: Heat-mediated antigen retrieval (in citrate buffer pH 6) is required for immunohistochemical stainings

Data sheet hs-375_003.pdf
Important information
This product belongs to the HistoSure product line of antibodies developed for and extensively tested in FFPE tissues.
For more information please visit our HistoSure brand website.

References for CD11c - HS-375 003

STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI.
Olde Heuvel F, Holl S, Chandrasekar A, Li Z, Wang Y, Rehman R, Förstner P, Sinske D, Palmer A, Wiesner D, Ludolph A, et al.
Brain, behavior, and immunity (2019) 81: 228-246. HS-375 003 IHC; tested species: mouse
Cat. No.: HS-375 003
Quantity: 200 µl
Price: $370.00
STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI.
Olde Heuvel F, Holl S, Chandrasekar A, Li Z, Wang Y, Rehman R, Förstner P, Sinske D, Palmer A, Wiesner D, Ludolph A, et al.
Brain, behavior, and immunity (2019) 81: 228-246. HS-375 003 IHC; tested species: mouse
Background
CD 11c or Integrin alpha-X (ITGAX) is a heterodimeric glycoprotein consisting of an α- and β-subunit and has seven repeating integrin domains. This transmembrane receptor type I plays a pivotal role in T cell killing and mediates intercellular adhesions during inflammation. Predominat expression levels have been found in dendritic cells, monocytes, macrophages, neutrophils and a small subset of B cells. Under pathological conditions, CD 11c is a marker for hairy cell leukemia, acute non-lymphocytic leukemias, and some chronic lymphocytic leukemias.
Protocols