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CD11c antibody - HS-375 004

CD11c is a fibrinogen receptor involved in cell-cell interaction during inflammation
Polyclonal Guinea pig antiserum
Cat. No.: HS-375 004
Amount: 100 µl
Price: $350.00
Cat. No. HS-375 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications IHC: 1 : 1000 gallery  
IHC-P/FFPE: 1 : 500 up to 1 : 2000 gallery  
Immunogen Synthetic peptide corresponding to AA 1159 to 1169 from mouse CD11c (UniProt Id: Q9QXH4)
Reactivity Reacts with: mouse (Q9QXH4).
Other species not tested yet.
Specificity Specific for CD11c.
Matching control protein/peptide 375-0P
Data sheet hs-375_004.pdf
Important information
This product belongs to the HistoSure product line of antibodies developed for and extensively tested in FFPE tissues.
For more information please visit our HistoSure brand website.
Cat. No.: HS-375 004
Quantity: 100 µl
Price: $350.00
Background
CD 11c or Integrin alpha-X (ITGAX) is a heterodimeric glycoprotein consisting of an α- and β-subunit and has seven repeating integrin domains. This transmembrane receptor type I plays a pivotal role in T cell killing and mediates intercellular adhesions during inflammation. Predominat expression levels have been found in dendritic cells, monocytes, macrophages, neutrophils and a small subset of B cells. Under pathological conditions, CD 11c is a marker for hairy cell leukemia, acute non-lymphocytic leukemias, and some chronic lymphocytic leukemias.
Protocols