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Home > Products > 506 017

TMEM106B antibody - 506 017 K.O.

TMEM106B forms amyloid-like fibrils in human brain
Rat monoclonal purified IgG
Cat. No.: 506 017
Amount: 100 µg
Price: $420.00
Cat. No. 506 017 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: 1 : 1000 up to 1 : 2000 (see remarks) gallery  
Clone SY-118C4
Subtype IgG2a (κ light chain)
Immunogen Synthetic peptide corresponding to AA 239 to 252 from human TMEM106B (UniProt Id: Q9NUM4)
Epitop AA 239 to 252 from human TMEM106B (UniProt Id: Q9NUM4)
Reactivity Reacts with: human (Q9NUM4), mouse (Q80X71).
Other species not tested yet.
Specificity K.O. validated
Remarks

WB: This antibody shows an additional unspecific band at 70kD.
IHC-P: 80% formic acid for 10min and heat mediated antigen retrieval (Tris/EDTA pH 9,0) is recommended for immunohistochemical staining.
Data sheet 506_017.pdf

References for TMEM106B - 506 017

Physiological shedding and C-terminal proteolytic processing of TMEM106B.
Held S, Erck C, Kemppainen S, Bleibaum F, Giridhar NJ, Feederle R, Krenner C, Juopperi SP, Calliari A, Mentrup T, Schröder B, et al.
Cell reports (2024) 441: 115107. 506 017 WB, IHC-P; tested species: human,mouse
Cat. No.: 506 017
Amount: 100 µg
Price: $420.00
WB
IHC-P