|Cat. No. 485 004||
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: not tested yet
Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: 1 : 500 gallery
Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.', $event)" style="cursor: help;">IHC-P: 1 : 1000 gallery
|Immunogen||Synthetic peptide corresponding to residues near the carboxy terminus of human FoxP2. (UniProt Id: O15409)|
Reacts with: mouse (P58463), rat (P0CF24).
Other species not tested yet.
Forkhead box protein P2, FoxP2 is a transcription factor protein that belongs to the family of winged-helix DNA binding proteins known as the Fox family (1). The FoxP subclass comprises four members, FoxP1-4 (2). FoxP3 is mainly expressed in the immune system, while FoxP1, 2 and 4 occur in various tissues (2). In brain they are located to distinct cell types in a specific spatiotemporal pattern (2, 3). FoxP2 is involved in a wide range of biological processes, including neuronal and lung development (1). Mutations in the FOXP2 gene have been implicated in several human speech and language disorders (4). Consistent with these findings, FoxP2 was shown to play an important role in the transcriptional control of the SRXP2 gene that regulates synapse formation and vocalization in mice (5).