|Cat. No. 479 003||
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IP: not tested yet
Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: not tested yet
Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: not recommended
|Immunogen||Recombinant protein corresponding to AA 398 to 445 from mouse Kir2.3 (UniProt Id: P52189)|
Reacts with: mouse (P52189), rat (P52190).
Other species not tested yet.
|Specificity||Specific for Kir2.3|
The inward rectifier potassium channels of the Kir2 subfamily consists of Kir2-1 – Kir2.4. They are widely and differentially expressed in the mammalian brain (1, 2), and exhibit the strongest difference between cellular potassium uptake and outward currents (1, 3). Kir2 potassium channels modulate cellular excitability, membrane potential, and the secretion of neurotransmitters and hormones (3).