Cat. No.: 464 004
Amount: 100 µl
Price:
$365.00
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| Cat. No. 464 004 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 1 to 364 from human ALDOC (UniProt Id: P09972) |
| Reactivity |
Reacts with: mouse (P05063), rat (P09117). Other species not tested yet. |
| Specificity | Specific for Aldolase C, no cross-reactivity to Aldolase A and B. |
| Remarks |
ICC: Methanol fixation is recommended. |
| Data sheet | 464_004.pdf |
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Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. (1)
Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells (2). Aldolase C is also expressed in astrocytes (3)