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Aldolase C antibody - 464 004

Aldolase C a brain type isozyme of a glycolysis enzyme
Guinea pig polyclonal antiserum
Cat. No.: 464 004
Amount: 100 µl
Price: $350.00
Cat. No. 464 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: not recommended
Immunogen Recombinant protein corresponding to AA 1 to 364 from human ALDOC (UniProt Id: P09972)
Reactivity Reacts with: mouse (P05063), rat (P09117).
Other species not tested yet.
Specificity Specific for Aldolase C, no cross-reactivity to Aldolase A and B.
Remarks

ICC: Methanol fixation is recommended.

Data sheet 464_004.pdf
Cat. No.: 464 004
Amount: 100 µl
Price: $350.00
Background

Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. (1)
Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells (2). Aldolase C is also expressed in astrocytes (3)