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BCAS1 antibody - 445 011

BCAS1 is a protein specific for an actively myelinating oligodendrocyte subpopulation
Mouse monoclonal purified IgG
Cat. No.: 445 011
Amount: 100 µg
Price: $415.00
Cat. No. 445 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 1000 gallery  
Clone SY-203G7
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to C-terminal residues of mouse BCAS1. (UniProt Id: Q80YN3)
Reactivity Reacts with: mouse (Q80YN3), rat (Q3ZB98).
Other species not tested yet.
Specificity Specific for BCAS 1
Data sheet 445_011.pdf
Cat. No.: 445 011
Amount: 100 µg
Price: $415.00

Breast carcinoma-amplified sequence 1 (BCAS1) was originally identified as a potential oncogene amplified in human cancer cell lines (1). It is also highly expressed in brain (2) where it mainly defines an oligodendroglial subpopulation occuring at regions of active myelin formation (3).
In fetal brain BCAS1 positive oligodendrocytes are restricted to the white matter. In adult brains they persist in the grey matter until old age (3).