Cat. No.: 445 003
Amount: 50 µg
Price:
$380.00
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| Cat. No. 445 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 1 to 633 from mouse BCAS1 (UniProt Id: Q80YN3) |
| Reactivity |
Reacts with: mouse (Q80YN3), rat (Q3ZB98-1), human (O75363). Other species not tested yet. |
| Specificity | Specific for BCAS1 and its known isoforms |
| Remarks |
IHC: AGR can improve signal strength and reveals additional immunoreactive structures. |
| Data sheet | 445_003.pdf |
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Breast carcinoma-amplified sequence 1 (BCAS1) was originally identified as a potential oncogene amplified in human cancer cell lines (1). It is also highly expressed in brain (2) where it mainly defines an oligodendroglial subpopulation occuring at regions of active myelin formation (3).
In fetal brain BCAS1 positive oligodendrocytes are restricted to the white matter. In adult brains they persist in the grey matter until old age (3).