|Cat. No. 425 006||200 µl purified IgY, lyophilized. Ovalbumin was added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C until use. Before storing at -20°C add 1 vol of glycerol.|
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery
IHC-P/FFPE: 1 : 100 up to 1 : 250 (see remarks) gallery
|Immunogen||Recombinant protein corresponding to AA 489 to 614 from rat AChE (UniProt Id: P37136)|
Reacts with: rat (P37136), mouse (P21836).
Other species not tested yet.
|Specificity||Detects isoform T, may cross react to isoforms R and H.|
IHC: Antigen retrieval (10mM citrate, pH 6.0, overnight at 60°C) is recommended.
IHC-P: Antigen retrieval (10mM Tris, 1mM EDTA, pH 9.0) is recommended.
Acetylcholinesterase also known as AChE or Acetylhydrolase, hydrolyzes the neurotransmitter acetylcholine at neuromuscular junctions and cholinergic synapses in the brain and thus terminates signal transmission. The protein is also found on the membranes of erythrocytes.
Acetylcholinesterase is a globular, glycosylated protein that lacks a transmembrane peptide-anchor region and occurs as several isoforms, originating from alternative splicing of the AChE mRNA.