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MDGA 1 - 421 002

An IgSF protein involved in neural development
Polyclonal rabbit antiserum
Cat. No.: 421 002
Amount: 200 µl
Price: $350.00
Cat. No. 421 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 19 to 917 from mouse MDGA1 (UniProt Id: Q0PMG2)
Reactivity Reacts with: mouse (Q0PMG2).
Other species not tested yet.
Specificity Specific for MDGA 1. K.O.
Data sheet 421_002.pdf
Cat. No.: 421 002
Quantity: 200 µl
Price: $350.00
Background

MAM domain GPI anchor 1 and 2 proteins (MDGA1 and MDGA2) are Ig superfamily adhesion molecules composed of six IG domains, a fibronectin III domain, a MAM domain, and a GPI anchor.

MDGAs are required for radial migration and positioning of cortical neurons making it a useful layer and area specific marker during neural development.

They play a role in the formation or maintenance of Neuroligin2 positive inhibitory synapses.