|Cat. No. 420 011||100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.|
WB: not recommended
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery
IHC: 1 : 500 up to 1 : 5000 gallery
IHC-P/FFPE: not recommended
|Subtype||IgG2b (κ light chain)|
|Immunogen||Recombinant protein corresponding to AA 1 to 94 from human S100A1 (UniProt Id: P23297)|
Epitop: AA 1 to 94 from human S100A1 (UniProt Id: P23297)
Reacts with: mouse (P56565), rat (P35467).
Other species not tested yet.
|Specificity||Specific for S100A1, no cross-reactivity to S100A6 and S100B|
S100A1, also known as S100A, or S100 alpha, is a 10 kDa member of the S100 family and contains 2 EF-hand calcium-binding motifs. In contrast to S100B which is composed of two beta chains, S100A1 contains an alpha and a beta chain. It is expressed in heart, skeletal muscle and brain where it plays a major role in regulating calcium-dependent contractility.