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KCC 2 antibody - 393 004

KCC2 is an electroneutral potassium-chloride co-transporter
Guinea pig polyclonal antiserum
Cat. No.: 393 004
Amount: 100 µl
Price: $350.00
Cat. No. 393 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 932 to 1043 from rat KCC2 (UniProt Id: Q63633)
Reactivity Reacts with: mouse, rat (Q63633).
Other species not tested yet.
Specificity Recognizes KCC 2a and KCC 2b.
Data sheet 393_004.pdf
Cat. No.: 393 004
Amount: 100 µl
Price: $350.00
Background
KCC 2 is a potassium-chloride co-transporter that is exclusively expressed in neurons of the central nervous system. The electroneutral potassium-chloride co-transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. KCC 2 is important for Cl- homeostasis in neurons.
Two isoforms, KCC 2a and KCC 2b, have been described, so far.