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LAMP3 antibody - 391 004

LAMP3 is a glycoprotein of the lysosomal membrane
Guinea pig polyclonal antiserum
Cat. No.: 391 004
Amount: 100 µl
Price: $450.00
Cat. No. 391 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: not tested yet
Dot blot: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 2000 gallery  
IHC-P: 1 : 1000 up to 1 : 5000 gallery  
Immunogen Synthetic peptide corresponding to C-terminal residues of mouse LAMP3. (UniProt Id: Q7TST5)
Reactivity Reacts with: mouse (Q7TST5), rat (Q5XI99).
Other species not tested yet.
Specificity Recognizes LAMP 3, no crossreactivity to LAMP 1, LAMP 2 and LAMP 5.

Dot blot: This application was tested with synthetic peptides only.

Data sheet 391_004.pdf
Cat. No.: 391 004
Amount: 100 µl
Price: $450.00
LAMP 3 (lysosome-associated membrane glycoprotein 3), also referred to as DC-LAMP (dendritic cell LAMP) or CD 208, is a member of the LAMP protein family and a single-pass type I transmembrane protein that can be variably glycosylated. It is specifically expressed in lung type II pneumocytes and by activated human dendritic cells.
Recent studies demonstrated high expression of LAMP 3 in a variety of malignancies including squamous cell carcinoma, gastrointestinal cancer, breast cancer, ovarian cancer, and cervical cancer. Its expression has been associated with hypoxia-induced metastasis and poor overall survival.