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Calcineurin A - 387 002

 
Polyclonal rabbit antiserum
Cat. No.: 387 002
Amount: 200 µl
Price: $350.00
Cat. No. 387 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 2000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 1000 up to 1 : 5000 gallery  
IHC: 1 : 500 up to 1 : 5000      gallery  
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 521 from human Calcineurin (UniProt Id: Q08209)
Reactivity Reacts with: rat (P63329), mouse (P63328), human (Q08209).
Other species not tested yet.
Specificity Specific for Calcineurin A.
Matching control protein/peptide 387-0P
Data sheet 387_002.pdf
Cat. No.: 387 002
Quantity: 200 µl
Price: $350.00
Background
Calcineurin (PP2B) is a calcium/calmodulin dependent Ser/Thr protein phosphatase that is expressed at high levels in the CNS. It is a heterodimeric protein consisting of a catalytic subunit calcineurin A containing an active site dinuclear metal center, and a tightly associated, myristoylated, Ca2+-binding subunit called calcineurin B. Calcineurin is involved in many cellular processes and Ca2+-dependent signal transduction pathways.