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TRIM 46 - 377 011

A protein involved in establishing neuronal polarity
Monoclonal mouse purified antibody
Cat. No.: 377 011
Amount: 100 µg
Price: $415.00
Cat. No. 377 011 100 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: 1 : 250 gallery  
IHC: 1 : 100 gallery  
IHC-P/FFPE: 1 : 100 gallery  
Clone 264D12
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 561 from rat Trim46 (UniProt Id: A0A0G2JXN2)
Epitop Epitop: AA 1 to 561 from rat Trim46 (UniProt Id: A0A0G2JXN2)
Reactivity Reacts with: mouse (Q7TNM2), rat (A0A0G2JXN2).
Other species not tested yet.
Specificity Specific for TRIM 46
Data sheet 377_011.pdf
Cat. No.: 377 011
Quantity: 100 µg
Price: $415.00
Background
The tripartite motif containing protein TRIM 46, also referred to as TRIFIC, is a member of the C-I TRIM family, a subfamily of the RBCC (N-terminal RING finger/B-box/coiled coil)/TRIM superfamily.
TRIM 46 localizes to newly specified axons and, at later stages, to the axon initial segment (AIS). By forming closely spaced parallel microtubule bundles it plays a crucial role in the initial polarization of neuronal cells.