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DOPA decarboxylase antibody - 369 011

An enzyme for dopamine, serotonin, and trace amine biosynthesis
Monoclonal mouse purified IgG
Cat. No.: 369 011
Amount: 100 µg
Price: $415.00
Cat. No. 369 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 5000 gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Clone 126F10
Subtype IgG2b (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 480 from mouse DDC (UniProt Id: O88533)
Reactivity Reacts with: mouse (O88533), rat (P14173).
Other species not tested yet.
Specificity Specific for DOPA decarboxylase
Data sheet 369_011.pdf
Cat. No.: 369 011
Quantity: 100 µg
Price: $415.00
Background

DOPA decarboxylase, also referred to as aromatic L-amino acid decarboxylase, AADC or DDC, is the second enzyme in the biosynthesis of dopamine and serotonin. In addition, it is responsible for the synthesis of the trace amines phenylethylamine, p-tyramine, and tryptamine, which are considered to act as neuromodulators.
DDC is expressed in the central nervous system, but has also been detected in several tissues such as liver, kidney, small intestine, adrenal gland and blood vessels.
The inhibition of DDC is used for the treatment of Parkinson's disease.