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Home > Products > 366 006

Somatostatin-28 antibody - 366 006

SST is a peptide hormone with inhibitory functions
Chicken polyclonal purified antibody
Cat. No.: 366 006
Amount: 200 µl
Price: $380.00
Cat. No. 366 006 200 µl specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 500 up to 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 89 to 100 from mouse Somatostatin (UniProt Id: P60041)
Reactivity Reacts with: rat (P60042), mouse (P60041).
Other species not tested yet.
Specificity This antibody preferentially recognizes somatostatin-28. It only shows minor cross-reactivity to the unprocessed precursor protein and does not detect somatostatin-14.
Data sheet 366_006.pdf

References for Somatostatin-28 - 366 006

Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption.
Mathisen AF, Larsen U, Kavli N, Unger L, Daian LM, Vacaru AM, Vacaru AM, Herrera PL, Ghila L, Chera S
Communications biology (2024) 71: 833. 366 006 IHC; tested species: mouse
Purkinje cell microzones mediate distinct kinematics of a single movement.
Blot FGC, White JJ, van Hattem A, Scotti L, Balaji V, Adolfs Y, Pasterkamp RJ, De Zeeuw CI, Schonewille M
Nature communications (2023) 141: 4358. 366 006 IHC; tested species: mouse
Amygdala inhibitory neurons as loci for translation in emotional memories.
Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E
Nature (2020) 5867829: 407-411. 366 006 IHC; tested species: mouse
Cat. No.: 366 006
Amount: 200 µl
Price: $380.00
Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption.
Mathisen AF, Larsen U, Kavli N, Unger L, Daian LM, Vacaru AM, Vacaru AM, Herrera PL, Ghila L, Chera S
Communications biology (2024) 71: 833. 366 006 IHC; tested species: mouse
Purkinje cell microzones mediate distinct kinematics of a single movement.
Blot FGC, White JJ, van Hattem A, Scotti L, Balaji V, Adolfs Y, Pasterkamp RJ, De Zeeuw CI, Schonewille M
Nature communications (2023) 141: 4358. 366 006 IHC; tested species: mouse
Amygdala inhibitory neurons as loci for translation in emotional memories.
Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E
Nature (2020) 5867829: 407-411. 366 006 IHC; tested species: mouse
ICC
IHC
IHC-P
Background
Somatostatin, also referred to as SST, growth hormone-inhibiting hormone or GHIH, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors. It inhibits the secretion of many important hormones, including insulin, glucagon and somatotropin (also designated growth hormone, or GH).
Somatostatin has two forms, active 14 amino acid and 28 amino acid. They are produced by alternative cleavage of the single precursor protein encoded by this gene.
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