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CD31 - 351 004

An endothelial cell marker
Polyclonal Guinea pig antiserum
Cat. No.: 351 004
Amount: 100 µl
Price: $350.00
Cat. No. 351 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: 1 : 200 up to 1 : 500     gallery  
Immunogen Recombinant protein corresponding to AA 26 to 601 from human CD31 (UniProt Id: P16284)
Reactivity Reacts with: human (P16284).
No signal: mouse (Q08481).
Other species not tested yet.
Specificity Specific for CD 31; detects all five isoforms.
Data sheet 351_004.pdf

References for CD31 - 351 004

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, et al.
Neuron (2019) : . 351 004 IHC; tested species: human
Role of A Novel Angiogenesis FKBPL-CD44 Pathway in Preeclampsia Risk Stratification and Mesenchymal Stem Cell Treatment.
Todd N, McNally R, Alqudah A, Jerotic D, Suvakov S, Obradovic D, Hoch D, Hombrebueno JR, Campos GL, Watson CJ, Gojnic-Dugalic M, et al.
The Journal of clinical endocrinology and metabolism (2021) 1061: 26-41. 351 004 IHC-P; tested species: human
CD8+ T cells target cerebrovasculature in children with cerebral malaria.
Riggle BA, Manglani M, Maric D, Johnson KR, Lee MH, Lopes Abath Neto O, Taylor TE, Seydel KB, Nath A, Miller LH, McGavern DB, et al.
The Journal of clinical investigation (2019) : . 351 004 IHC-P; tested species: human
Cat. No.: 351 004
Quantity: 100 µl
Price: $350.00
Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, et al.
Neuron (2019) : . 351 004 IHC; tested species: human
Role of A Novel Angiogenesis FKBPL-CD44 Pathway in Preeclampsia Risk Stratification and Mesenchymal Stem Cell Treatment.
Todd N, McNally R, Alqudah A, Jerotic D, Suvakov S, Obradovic D, Hoch D, Hombrebueno JR, Campos GL, Watson CJ, Gojnic-Dugalic M, et al.
The Journal of clinical endocrinology and metabolism (2021) 1061: 26-41. 351 004 IHC-P; tested species: human
CD8+ T cells target cerebrovasculature in children with cerebral malaria.
Riggle BA, Manglani M, Maric D, Johnson KR, Lee MH, Lopes Abath Neto O, Taylor TE, Seydel KB, Nath A, Miller LH, McGavern DB, et al.
The Journal of clinical investigation (2019) : . 351 004 IHC-P; tested species: human
Background
CD 31 or PECAM 1 is a cell adhesion molecule that contains a single trans-membrane domain and 6 Ig-like C2-type (immunoglobulin-like) domains. It is expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Five isoforms (long-form and δ 12, 13, 14 and 15) with differential expression patterns have been described, so far.