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Home > Products > 340 004

SERT antibody - 340 004

SERT translocates serotonin back from the synaptic cleft into the presynaptic neuron
Guinea pig polyclonal antiserum
Cat. No.: 340 004
Amount: 100 µl
Price: $365.00
Cat. No. 340 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: not tested yet
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 77 from mouse SERT (UniProt Id: Q60857)
Reactivity Reacts with: rat (P31652), mouse (Q60857).
Other species not tested yet.
Data sheet 340_004.pdf

References for SERT - 340 004

A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, et al.
Cell (2022) 18518: 3390-3407.e18. 340 004 ICC, IHC; tested species: mouse
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, et al.
Cell (2022) 18518: 3390-3407.e18. 340 004 ICC, IHC; tested species: mouse
Vortioxetine attenuates the effects of early-life stress on depression-like behaviors and monoamine transporters in female mice.
Liu X, Sun YX, Zhang CC, Zhang XQ, Zhang Y, Wang T, Ma YN, Wang H, Su YA, Li JT, Si TM, et al.
Neuropharmacology (2021) : 108468. 340 004 IHC; tested species: mouse
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.
Sellnow RC, Newman JH, Chambers N, West AR, Steece-Collier K, Sandoval IM, Benskey MJ, Bishop C, Manfredsson FP
Acta neuropathologica communications (2019) 71: 8. 340 004 IHC; tested species: rat
Cat. No.: 340 004
Amount: 100 µl
Price: $365.00
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, et al.
Cell (2022) 18518: 3390-3407.e18. 340 004 ICC, IHC; tested species: mouse
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, et al.
Cell (2022) 18518: 3390-3407.e18. 340 004 ICC, IHC; tested species: mouse
Vortioxetine attenuates the effects of early-life stress on depression-like behaviors and monoamine transporters in female mice.
Liu X, Sun YX, Zhang CC, Zhang XQ, Zhang Y, Wang T, Ma YN, Wang H, Su YA, Li JT, Si TM, et al.
Neuropharmacology (2021) : 108468. 340 004 IHC; tested species: mouse
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.
Sellnow RC, Newman JH, Chambers N, West AR, Steece-Collier K, Sandoval IM, Benskey MJ, Bishop C, Manfredsson FP
Acta neuropathologica communications (2019) 71: 8. 340 004 IHC; tested species: rat
IHC
IHC-P
Background
This serotonin transporter (SERT), also referred to as 5HTT and Slc6a4, is a monoamine transporter protein that transports serotonin back from the synaptic cleft into the presynaptic neuron to terminate the action of this neurotransmitter.
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