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Doublecortin - 326 006

A protein associated with neuronal differentiation
Polyclonal chicken purified antibody
Cat. No.: 326 006
Amount: 50 µg
Price: 370.00 €
Cat. No. 326 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Ovalbumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 1000 up to 1 : 2000 gallery  
IHC-P/FFPE: 1 : 2000 gallery  
Immunogen Recombinant protein corresponding to AA 271 to 366 from mouse Doublecortin (UniProt Id: Q6PGI2)
Epitop Epitop: AA 271 to 366 from mouse Doublecortin (UniProt Id: Q6PGI2)
Reactivity Reacts with: mouse (Q6PGI2).
Other species not tested yet.
Specificity specific for Doublecortin
Data sheet 326_006.pdf
Cat. No.: 326 006
Quantity: 50 µg
Price: 370.00 €
Background
Doublecortin or DCX seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. Mutations in the gene encoding this protein have been linked to the double cortex syndrome.
Doublecortin is highly expressed in neuronal cells of fetal brain but absent from other tissues. In the adult dentate gyrus it is only expressed in cells contributing to adult neurogenesis.