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ADAM 22 - 317 005

An ADAM family member involved in synaptic signal transmission
Polyclonal Guinea pig purified antibody
Cat. No.: 317 005
Amount: 50 µg
Price: $450.00
Cat. No. 317 005 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500      gallery  
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 775 to 905 from mouse ADAM22 (UniProt Id: Q9R1V6)
Reactivity Reacts with: rat, mouse (Q9R1V6).
Other species not tested yet.
Specificity Specific for ADAM 22.
Data sheet 317_005.pdf
Cat. No.: 317 005
Quantity: 50 µg
Price: $450.00
Background
ADAMs (a disintegrin and metalloproteinases) are a family of multidomain transmembrane glycoproteins.
With few exceptions most ADAM proteins are active zinc metalloproteinases. Members that lack functional metalloproteinase domains are implicated in protein-protein interactions instead of membrane protein ectodomain shedding. ADAM 22, one of these non-proteinase ADAMs acts as a receptor on the surface of the postsynaptic neuron and is involved in the regulation of synaptic signal transmission.