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Tau - 314 111

A microtubule associated protein
Monoclonal mouse purified IgG
Cat. No.: 314 111
Amount: 100 µg
Price: $415.00
Cat. No. 314 111 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 1000 up to 1 : 2000      gallery  
Clone 110G12
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 44 from human TauE (UniProt Id: P10636-7)
Epitop Epitop: AA 1 to 44 from human TauE (UniProt Id: P10636-7)
Reactivity Reacts with: human (P10636-7).
Other species not tested yet.
Specificity Specific for tau. This antibody binds phosphorylated and non-phosphorylated tau proteins.
Data sheet 314_111.pdf
Cat. No.: 314 111
Quantity: 100 µg
Price: $415.00
Background

There are two major classes of heat stable microtubule associated proteins (MAPS): MAP 2 (280 kD), and tau (55-65 kD). Both protein classes are involved in the regulation of microtubule polymerization in cells. Tau is a neuronal protein that mainly localizes to axons. Hyperphosphorylated tau has been shown to be a major element of paired helical filaments in Alzheimer's disease.