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Tau - 314 012

A microtubule associated protein
Polyclonal rabbit antiserum
Cat. No.: 314 012
Amount: 200 µl
Price: $350.00
Cat. No. 314 012 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: 1 : 500 up to 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 44 from human TauE (UniProt Id: P10636-7)
Reactivity Reacts with: human (P10636).
Other species not tested yet.
Specificity Specific for tau.
Remarks

The antibody binds phosphorylated and non-phosphorylated tau proteins. This antibody is highly recommended for human tissue.

Data sheet 314_012.pdf
Cat. No.: 314 012
Quantity: 200 µl
Price: $350.00
Background

There are two major classes of heat stable microtubule associated proteins (MAPS): MAP 2 (280 kD), and tau (55-65 kD). Both protein classes are involved in the regulation of microtubule polymerization in cells. Tau is a neuronal protein that mainly localizes to axons. Hyperphosphorylated tau has been shown to be a major element of paired helical filaments in Alzheimer's disease.